Oxidative damage as a fundament of systemic toxicities induced by cisplatin—the crucial limitation or potential therapeutic target?
JS Katanić Stanković, D Selaković, G Rosić - International journal of …, 2023 - mdpi.com
Cisplatin, an inorganic complex of platinum, is a chemotherapeutic drug that has been used
for 45 years. Despite the progress of pharmaceutical sciences and medicine and the …
for 45 years. Despite the progress of pharmaceutical sciences and medicine and the …
Current progress in stem cell therapy for male infertility
RF Adriansyah, R Margiana, S Supardi… - Stem Cell Reviews and …, 2023 - Springer
Infertility has become one of the most common issues worldwide, which has negatively
affected society and infertile couples. Meanwhile, male infertility is responsible for about …
affected society and infertile couples. Meanwhile, male infertility is responsible for about …
[HTML][HTML] Fenofibrate and Diosmetin in a rat model of testicular toxicity: New insight on their protective mechanism through PPAR-α/NRF-2/HO-1 signaling pathway
One of the most significant chemotherapeutic side effects of cisplatin (Cis) that limits its use
and efficacy is testicular toxicity. Thus, the objective of the present study was to investigate …
and efficacy is testicular toxicity. Thus, the objective of the present study was to investigate …
Alkylating agents‐induced gonadotoxicity in prepubertal males: insights on the clinical and preclinical front
S Sriram, T Macedo… - Clinical and …, 2024 - Wiley Online Library
Rising cure rates in pediatric cancer patients warrants an increased attention toward the
long‐term consequences of the diagnosis and treatment in survivors. Chemotherapeutic …
long‐term consequences of the diagnosis and treatment in survivors. Chemotherapeutic …
Combined laser-activated SVF and PRP remodeled spinal sclerosis via activation of Olig-2, MBP, and neurotrophic factors and inhibition of BAX and GFAP
A single injection of platelet-rich plasma (PRP) or stromal vascular fraction (SVF) in treating
neurological ailments suggests promise; however, there is limited evidence of the efficacy of …
neurological ailments suggests promise; however, there is limited evidence of the efficacy of …
The mollifying effect of Sambucus nigra extract on StAR gene expression, oxidative stress, and apoptosis induced by fenpropathrin in male rats
Fenpropathrin (FNP) is a man-made insecticide of to the pyrethroid class, commonly
employed in agricultural and horticultural practices. However, it has a prolonged persistence …
employed in agricultural and horticultural practices. However, it has a prolonged persistence …
Roles of adipose-derived stem cells and derived exosomes in therapeutic applications to testicular injury caused by cisplatin
S Wu, K Lv, T Zheng, T Zhang, Y Nan, R Wang - Plos one, 2024 - journals.plos.org
In recent years, adipose-derived stem cells (ADSCs) and derived exosomes (ADSC-Ex)
have been investigated for their therapeutic potential in various diseases due to their …
have been investigated for their therapeutic potential in various diseases due to their …
Polydatin, a derivative of resveratrol, ameliorates busulfan-induced oligozoospermia in mice by inhibiting NF-κB pathway activation and suppressing ferroptosis
C Wang, X Li, T Ye, J Gu, Z Zheng, G Chen, J Dong… - Bioorganic …, 2025 - Elsevier
Polydatin (PD), a glucoside derivative of resveratrol (RES), is extracted as a monomer
compound from the dried rhizome of Polygonum cuspidatum. Our laboratory synthesized PD …
compound from the dried rhizome of Polygonum cuspidatum. Our laboratory synthesized PD …
Mitigative Effects of l-Arginine and N-Acetyl Cysteine against Cisplatin-Induced Testicular Dysfunction and Toxicity through the Regulation of Antioxidant, Anti …
FA Gad, M Abdelghaffar Emam, AA Eldeeb… - ACS …, 2024 - ACS Publications
Testicular dysfunction is a common adverse effect of cisplatin (CIS) administration as a
chemotherapeutic drug. The current study has outlined the role of micro-RNAs (miR-155 and …
chemotherapeutic drug. The current study has outlined the role of micro-RNAs (miR-155 and …