Epilepsy is a network disorder and each type of seizure involves distinct cortical and
subcortical network, differently implicated in the control and propagation of the ictal activity …

Bipolar disorder (BD) is a serious mental disorder involving widespread abnormal
interactions between brain regions, and it is believed to be associated with imbalanced …

The importance of self-feedback autaptic transmission in modulating spike-time irregularity
is still poorly understood. By using a biophysical model that incorporates autaptic coupling …

In this paper, we introduce general distributed delays (in pathways between different
neurons) and self-feedback distributed delays (in self-feedback pathways) into an improved …

Presently, we develop a simplified corticothalamic (SCT) model and propose a single-pulse
alternately resetting stimulation (SARS) with sequentially applying anodic (A,“+”) or cathodic …

Background and Purpose There is accumulating evidence that epilepsy is caused by
network dysfunction. We evaluated the hub reorganization of subcortical structures in …

This paper aims to analyze possible mechanisms underlying the generation of generalized
periodic epileptiform discharges (GPEDs), especially to design targeted optogenetic …

Excessively high, neural synchronization has been associated with epileptic seizures, one of
the most common brain diseases worldwide. A better understanding of neural …

Motivated by the recent experimental findings that thalamic reticular nucleus (TRN) may be a
pacemaker of absence seizures, we explore whether changes in the level of TRN activation …

Absence seizures are characterized by brief interruptions of conscious experience
accompanied by oscillations of activity synchronized across many brain areas. Although the …