Immunoinformatics design of a novel epitope-based vaccine candidate against dengue virus
AO Fadaka, NRS Sibuyi, DR Martin, M Goboza… - Scientific reports, 2021 - nature.com
Dengue poses a global health threat, which will persist without therapeutic intervention.
Immunity induced by exposure to one serotype does not confer long-term protection against …
Immunity induced by exposure to one serotype does not confer long-term protection against …
In silico modeling as a perspective in developing potential vaccine candidates and therapeutics for COVID-19
The potential of computational models to identify new therapeutics and repurpose existing
drugs has gained significance in recent times. The current 'COVID-19'pandemic caused by …
drugs has gained significance in recent times. The current 'COVID-19'pandemic caused by …
State of the art in epitope mapping and opportunities in COVID-19
The understanding of any disease calls for studying specific biological structures called
epitopes. One important tool recently drawing attention and improving efficiency in both …
epitopes. One important tool recently drawing attention and improving efficiency in both …
Designing a Recombinant Vaccine against Providencia rettgeri Using Immunoinformatics Approach
Antibiotic resistance (AR) is the resistance mechanism pattern in bacteria that evolves over
some time, thus protecting the bacteria against antibiotics. AR is due to bacterial evolution to …
some time, thus protecting the bacteria against antibiotics. AR is due to bacterial evolution to …
[HTML][HTML] Potential inhibitors of SARS-CoV-2 (COVID 19) proteases PLpro and Mpro/3CLpro: molecular docking and simulation studies of three pertinent medicinal …
The rapid spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-
coronavirus disease 2019 (COVID-19) has raised a severe global public health issue and …
coronavirus disease 2019 (COVID-19) has raised a severe global public health issue and …
Multi-epitope peptide vaccines targeting dengue virus serotype 2 created via immunoinformatic analysis
RN Morgan, NSM Ismail, MY Alshahrani… - Scientific Reports, 2024 - nature.com
Abstract The Middle East has witnessed a greater spread of infectious Dengue viruses, with
serotype 2 (DENV-2) being the most prevalent form. Through this work, multi-epitope …
serotype 2 (DENV-2) being the most prevalent form. Through this work, multi-epitope …
Landscape and selection of vaccine epitopes in SARS-CoV-2
Background Early in the pandemic, we designed a SARS-CoV-2 peptide vaccine containing
epitope regions optimized for concurrent B cell, CD4+ T cell, and CD8+ T cell stimulation …
epitope regions optimized for concurrent B cell, CD4+ T cell, and CD8+ T cell stimulation …
Development of a multi-epitope vaccine candidate for leishmanial parasites applying immunoinformatics and in vitro approaches
Leishmaniasis is a neglected tropical disease, and its severity necessitates the development
of a potent and efficient vaccine for the disease; however, no human vaccine has yet been …
of a potent and efficient vaccine for the disease; however, no human vaccine has yet been …
An Immunoinformatics Approach to Design a Potent Multi-Epitope Vaccine against Asia-1 Genotype of Crimean–Congo Haemorrhagic Fever Virus Using the …
Crimean–Congo haemorrhagic fever (CCHF), caused by Crimean–Congo haemorrhagic
fever virus (CCHFV), is a disease of worldwide importance (endemic yet not limited to Asia …
fever virus (CCHFV), is a disease of worldwide importance (endemic yet not limited to Asia …
Coevolution based immunoinformatics approach considering variability of epitopes to combat different strains: A case study using spike protein of SARS-CoV-2
In the recent past several vaccines were developed to combat the COVID-19 disease.
Unfortunately, the protective efficacy of the current vaccines has been reduced due to the …
Unfortunately, the protective efficacy of the current vaccines has been reduced due to the …