Immune cells in head-and-neck tumor microenvironments

E Jumaniyazova, A Lokhonina, D Dzhalilova… - Journal of Personalized …, 2022 - mdpi.com
Head-and-neck cancers constitute a heterogeneous group of aggressive tumors with high
incidence and low survival rates, collectively being the sixth most prevalent cancer type …

[HTML][HTML] Statistics and network-based approaches to identify molecular mechanisms that drive the progression of breast cancer

MS Alam, MM Rahaman, A Sultana, G Wang… - Computers in Biology …, 2022 - Elsevier
Breast cancer (BC) is one of the most malignant tumors and the leading cause of cancer-
related death in women worldwide. So, an in-depth investigation on the molecular …

Computational identification of host genomic biomarkers highlighting their functions, pathways and regulators that influence SARS-CoV-2 infections and drug …

MP Mosharaf, MS Reza, MK Kibria, FF Ahmed… - Scientific reports, 2022 - nature.com
The pandemic threat of COVID-19 has severely destroyed human life as well as the
economy around the world. Although, the vaccination has reduced the outspread, but …

Network-based approach to identify molecular signatures and therapeutic agents in Alzheimer's disease

MR Rahman, T Islam, B Turanli, T Zaman… - … biology and chemistry, 2019 - Elsevier
Alzheimer's disease (AD) is a dynamic degeneration of the brain with progressive dementia.
Considering the uncertainties in its molecular mechanism, in the present study, we …

Genome-scale metabolic models in translational medicine: the current status and potential of machine learning in improving the effectiveness of the models

B Turanli, G Gulfidan, OO Aydogan, C Kula… - Molecular …, 2024 - pubs.rsc.org
The genome-scale metabolic model (GEM) has emerged as one of the leading modeling
approaches for systems-level metabolic studies and has been widely explored for a broad …

Identification of host transcriptome-guided repurposable drugs for SARS-CoV-1 infections and their validation with SARS-CoV-2 infections by using the integrated …

FF Ahmed, MS Reza, MS Sarker, MS Islam… - PLoS …, 2022 - journals.plos.org
Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is one of the most severe
global pandemic due to its high pathogenicity and death rate starting from the end of 2019 …

Integrated bioinformatics and statistical approaches to explore molecular biomarkers for breast cancer diagnosis, prognosis and therapies

MS Alam, A Sultana, MS Reza, M Amanullah, SR Kabir… - PloS one, 2022 - journals.plos.org
Integrated bioinformatics and statistical approaches are now playing the vital role in
identifying potential molecular biomarkers more accurately in presence of huge number of …

Identification of prognostic biomarker signatures and candidate drugs in colorectal cancer: insights from systems biology analysis

MR Rahman, T Islam, E Gov, B Turanli, G Gulfidan… - Medicina, 2019 - mdpi.com
Background and objectives: Colorectal cancer (CRC) is the second most common cause of
cancer-related death in the world, but early diagnosis ameliorates the survival of CRC. This …

Robust identification of common genomic biomarkers from multiple gene expression profiles for the prognosis, diagnosis, and therapies of pancreatic cancer

MB Hossen, MA Islam, MS Reza, MK Kibria… - Computers in Biology …, 2023 - Elsevier
Pancreatic cancer (PC) is one of the leading causes of cancer-related death globally. So,
identification of potential molecular signatures is required for diagnosis, prognosis, and …

MicroRNA expression patterns in oral squamous cell carcinoma: hsa‐mir‐99b‐3p and hsa‐mir‐100‐5p as novel prognostic markers for oral cancer

M Jakob, LM Mattes, S Küffer, K Unger, J Hess… - Head & …, 2019 - Wiley Online Library
Background MicroRNAs (miRNA) recently evolved as potential cancer biomarkers.
Therefore, the aim of the present study was to evaluate the prognostic impact of eight …