“Organ‐on‐a‐chip” systems integrate microengineering, microfluidic technologies, and
biomimetic principles to create key aspects of living organs faithfully, including critical …

Nanomedicine involves the use of engineered nanoscale materials in an extensive range of
diagnostic and therapeutic applications and can be applied to the treatment of many …

The spleen clears altered red blood cells (RBCs) from circulation, contributing to the balance
between RBC formation (erythropoiesis) and removal. The splenic RBC retention and …

In recent years, the exploitation of phenomena surrounding microfluidics has seen an
increase in popularity, as researchers have found a way to use their unique properties to …

Research on microbial pathogens has traditionally relied on animal and cell culture models
to mimic infection processes in the host. Over recent years, developments in microfluidics …

Red blood cells (RBCs) are deformable and flow through vessels narrower than their own
size. Their deformability is most stringently challenged when they cross micrometer‐wide …

The number of successful drug development projects has been stagnant for decades
despite major breakthroughs in chemistry, molecular biology, and genetics. Unreliable target …

Combining microfluidics technology with machine learning represents an innovative
approach to conduct massive quantitative cell behavior study and implement smart decision …

Highlights•Immune system plays a critical role in maintaining homeostasis of the human
body.•Development of immune-system-on-a-chip platforms is in its infancy.•Several …

There are fundamental differences between humans and the animals we typically use to
study the immune system. We have learned much from genetically manipulated and inbred …