Role of oxidative stress in the pathogenesis of nonalcoholic fatty liver disease

Z Chen, R Tian, Z She, J Cai, H Li - Free Radical Biology and Medicine, 2020 - Elsevier
Nonalcoholic fatty liver disease (NAFLD) has emerged as the most common chronic liver
disease worldwide and is strongly associated with the presence of oxidative stress …

Molecular mechanisms that link oxidative stress, inflammation, and fibrosis in the liver

E Ramos-Tovar, P Muriel - Antioxidants, 2020 - mdpi.com
Activated hepatic stellate cells (HSCs) and myofibroblasts are the main producers of
extracellular matrix (ECM) proteins that form the fibrotic tissue that leads to hepatic fibrosis …

Transforming growth factor-β-induced cell plasticity in liver fibrosis and hepatocarcinogenesis

I Fabregat, D Caballero-Díaz - Frontiers in oncology, 2018 - frontiersin.org
The Transforming Growth Factor-beta (TGF-β) family plays relevant roles in the regulation of
different cellular processes that are essential for tissue and organ homeostasis. In the case …

[HTML][HTML] European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)

J Egea, I Fabregat, YM Frapart, P Ghezzi, A Görlach… - Redox biology, 2017 - Elsevier
Abstract The European Cooperation in Science and Technology (COST) provides an ideal
framework to establish multi-disciplinary research networks. COST Action BM1203 (EU …

Metabolic hallmarks of hepatic stellate cells in liver fibrosis

O Khomich, AV Ivanov, B Bartosch - Cells, 2019 - mdpi.com
Liver fibrosis is a regenerative process that occurs after injury. It is characterized by the
deposition of connective tissue by specialized fibroblasts and concomitant proliferative …

[HTML][HTML] Oxidative stress and bronchopulmonary dysplasia

J Wang, W Dong - Gene, 2018 - Elsevier
With the progress of modern medicine, oxygen therapy has become a crucial measure for
the treatment of premature infants. As an environmental stimulus, in the normal development …

[HTML][HTML] Selenium deficiency-induced redox imbalance leads to metabolic reprogramming and inflammation in the liver

C Tang, S Li, K Zhang, J Li, Y Han, T Zhan, Q Zhao… - Redox biology, 2020 - Elsevier
Selenium (Se) intake disequilibrium is associated with many human diseases (eg, Keshan
disease and type 2 diabetes). To understand the mechanism of Se deficiency-induced …

[HTML][HTML] Mulberrin confers protection against hepatic fibrosis by Trim31/Nrf2 signaling

C Ge, J Tan, D Lou, L Zhu, Z Zhong, X Dai, Y Sun… - Redox biology, 2022 - Elsevier
Mulberrin (Mul) is a key component of the traditional Chinese medicine Romulus Mori with
various biological functions. However, the effects of Mul on liver fibrosis have not been …

[HTML][HTML] MicroRNAs in the regulation of cellular redox status and its implications in myocardial ischemia-reperfusion injury

T Carbonell, AV Gomes - Redox biology, 2020 - Elsevier
MicroRNAs (miRNAs) are small RNAs that do not encode for proteins and play key roles in
the regulation of gene expression. miRNAs are involved in a comprehensive range of …

[HTML][HTML] Reactive oxygen species and antioxidant system in selected skin disorders

JM Jaffri - The Malaysian journal of medical sciences: MJMS, 2023 - ncbi.nlm.nih.gov
The skin has a solid protective system that includes the stratum corneum as the primary
barrier and a complete antioxidant defence system to maintain the skin's normal redox …