Eyeing up the future of the pupillary light reflex in neurodiagnostics

CA Hall, RP Chilcott - Diagnostics, 2018 - mdpi.com
The pupillary light reflex (PLR) describes the constriction and subsequent dilation of the
pupil in response to light as a result of the antagonistic actions of the iris sphincter and …

Parasympathetic nervous system dysfunction, as identified by pupil light reflex, and its possible connection to hearing impairment

Y Wang, AA Zekveld, G Naylor, B Ohlenforst… - PloS one, 2016 - journals.plos.org
Context Although the pupil light reflex has been widely used as a clinical diagnostic tool for
autonomic nervous system dysfunction, there is no systematic review available to …

Pupil dynamics during bistable motion perception

JM Hupé, C Lamirel, J Lorenceau - Journal of vision, 2009 - jov.arvojournals.org
Pupil size not only varies to changes in illumination but is also modulated by several
cognitive factors, making it a potentially versatile physiological marker of cortical states. We …

Cholinergic deficiency in Alzheimer's and Parkinson's disease: evaluation with pupillometry

DF Fotiou, V Stergiou, D Tsiptsios, C Lithari… - International Journal of …, 2009 - Elsevier
The aim of the study was to evaluate the cholinergic deficiency in Alzheimer's (AD) and
Parkinson's disease (PD). For this purpose, pupil size changes and mobility were assessed …

Effects of vagus nerve stimulation on pupillary function

VD Jodoin, P Lespérance, DK Nguyen… - International Journal of …, 2015 - Elsevier
Background Chronic vagus nerve stimulation (VNS) is a recognized treatment for refractory
epilepsy and depression. The vagus nerve projects to several brainstem autonomic …

Pupil light reflex in Parkinson's disease: evaluation with pupillometry

E Giza, D Fotiou, S Bostantjopoulou… - International Journal …, 2011 - Taylor & Francis
We evaluated pupil light reflex (PLR) in patients with Parkinson's disease (PD) and normal
controls by means of pupillometry and explored its possible relation to clinical characteristics …

[HTML][HTML] Impact of stimulation duration in taVNS—exploring multiple physiological and cognitive outcomes

T Bömmer, LM Schmidt, K Meier, J Kricheldorff… - Brain Sciences, 2024 - mdpi.com
Transcutaneous auricular vagus nerve stimulation (taVNS) is a non-invasive
neuromodulation technique that modulates the noradrenergic activity of the locus coeruleus …

Pupil reaction to light in Alzheimer's disease: evaluation of pupil size changes and mobility

DF Fotiou, CG Brozou, AB Haidich, D Tsiptsios… - Aging clinical and …, 2007 - Springer
Aims: The aim of the study is to assess pupil size changes and mobility evaluation as a
diagnostic marker in patients with probable Alzheimer's disease (AD). Material and methods …

Psychological states affecting initial pupil size changes after olfactory stimulation in healthy participants

H Hatsukawa, M Ishikawa - Scientific Reports, 2023 - nature.com
Odor perception affects physiological and psychological states. Pupillary light reflex (PLR)
parameters can be affected by olfactory stimulation and psychological states, although it …

Tracking eye movements for diagnosis in myasthenia gravis: a comprehensive review

MNL Nguyen, A Van Der Walt, J Fielding… - Journal of Neuro …, 2022 - journals.lww.com
Background: Around 60%–-75% of myasthenia gravis (MG) patients initially present with
nonspecific ocular symptoms. Failed recognition of these symptoms may delay the diagnosis …