Tissue engineering of the tympanic membrane

BM Teh, RJ Marano, Y Shen, PL Friedland… - … Engineering Part B …, 2013 - liebertpub.com
Tympanic membrane (TM) perforations are common, with current treatments for chronic
perforations involving surgery, using various graft materials, from autologous cartilage or …

[HTML][HTML] Tissue engineering and regenerative medicine strategies for the repair of tympanic membrane perforations

E Sainsbury, R do Amaral, AW Blayney… - Biomaterials and …, 2022 - Elsevier
Despite the high success rate of autologous grafts in tympanic membrane repair, clinical
alternatives are required for the closure of unresponsive chronic perforations that can lead to …

A prospective study evaluating spontaneous healing of aetiology, size and type‐different groups of traumatic tympanic membrane perforation

ZC Lou, YM Tang, J Yang - Clinical Otolaryngology, 2011 - Wiley Online Library
Clin. Otolaryngol. 2011, 36, 450–460 Objectives: To evaluate the outcome of spontaneous
healing of aetiology‐, size‐and type‐different groups of acute traumatic eardrum perforation …

A new theory on the pathogenesis of acquired cholesteatoma: Mucosal traction

RK Jackler, PL Santa Maria, YK Varsak… - The …, 2015 - Wiley Online Library
Objectives/Hypothesis Although the migration of its squamous outer surface of the tympanic
membrane has been well characterized, there is a paucity of data available concerning the …

Multifaceted tannin crosslinked bioinspired dECM decorated nanofibers modulating cell–scaffold biointerface for tympanic membrane perforation bioengineering

Z Hussain, P Ding, L Zhang, Y Zhang, S Ullah… - Biomedical …, 2022 - iopscience.iop.org
Tympanic membrane (TM) perforation leads to persistent otitis media, conductive deafness,
and affects life quality. Ointment medication may not be sufficient to treat TM perforation …

Bacterial cellulose nanofibrillar patch as a wound healing platform of tympanic membrane perforation

J Kim, SW Kim, S Park, KT Lim… - Advanced …, 2013 - Wiley Online Library
Bacterial cellulose (BC)‐based biomaterials on medical device platforms have gained
significant interest for tissue‐engineered scaffolds or engraftment materials in regenerative …

Scaffolds for tympanic membrane regeneration in rats

Y Shen, SL Redmond, BM Teh, S Yan… - … engineering part A, 2013 - liebertpub.com
Tympanic membrane (TM) perforations lead to significant hearing loss and result in possible
infection of the middle ear. Myringoplasty is commonly performed to repair chronic …

Tympanic membrane repair using silk fibroin and acellular collagen scaffolds

Y Shen, SL Redmond, BM Teh, S Yan… - The …, 2013 - Wiley Online Library
Objectives/Hypothesis To evaluate the efficacy of silk fibroin scaffolds (SFS) and acellular
collagen scaffolds (ACS) for the repair of tympanic membrane (TM) in a guinea pig acute …

A review on the use of hyaluronic acid in tympanic membrane wound healing

BM Teh, Y Shen, PL Friedland, MD Atlas… - Expert opinion on …, 2012 - Taylor & Francis
Introduction: Tympanic membrane perforation represents a significant morbidity, especially if
it occurs during a child's speech and language development. Recently, there has been an …

Necessities, opportunities, and challenges for tympanic membrane perforation scaffolding-based bioengineering

Z Hussain, R Pei - Biomedical Materials, 2021 - iopscience.iop.org
Tympanic membrane (TM) perforation is a global clinical dilemma. It occurs as a
consequence of object penetration, blast trauma, barotrauma, and middle ear diseases. TM …