Platelets are small anucleated blood cells primarily known for their vital hemostatic role.
Allogeneic platelet concentrates (PCs) collected from healthy donors are an essential …

Circulating blood platelets play a central role in the maintenance of hemostasis. They
adhere to subendothelial extracellular matrix proteins that become exposed upon vessel …

Many studies have shown that endothelial dysfunction is associated with a variety of
cardiovascular diseases. The endothelium is one of the primary targets of circulating …

Human platelet lysates (HPLs) made from clinical-grade platelet concentrates are currently
evaluated in the preclinical models of Parkinson's disease, Alzheimer's disease, traumatic …

Platelets are anucleate cells that circulate in blood and are essential components of the
hemostatic system. During aging, platelet numbers decrease and their aggregation capacity …

Background Kawasaki disease (KD) is an acute vasculitis that may result in permanent
coronary artery damage with unknown etiology. Endothelial cell (EC) dysfunction and …

The haemostatic system is pivotal to maintaining vascular integrity. Multiple components
involved in blood coagulation have central functions in inflammation and immunity. A …

Pathogen inactivation (PI) for platelet concentrates (PC) is a fairly recent development in
transfusion medicine that is intended to decrease infectious disease transmission from the …

While platelets are traditionally recognized to play a predominant role in hemostasis and
thrombosis, increasing evidence verifies its involvement in malignancies. As a component of …

Background: Platelet concentrate (PC) is one of the main products used in a therapeutic
transfusion. This blood component requires special storage at blood banks, however, even …