New psychoactive substances (NPS) are a heterogeneous group of substances. They are
associated with a number of health and social harms on an individual and societal level …

Psychoactive substances with chemical structures or pharmacological profiles that are
similar to traditional drugs of abuse continue to emerge on the recreational drug market …

Dysregulation of the endogenous lipid mediators endocannabinoids and their G-protein-
coupled cannabinoid receptors 1 and 2 (CB1R and CB2R) has been implicated in a variety …

Background New psychoactive substances constitute a growing and dynamic class of
abused drugs in the United States. On July 12, 2016, a synthetic cannabinoid caused mass …

The word “cannabinoid” refers to every chemical substance, regardless of structure or origin,
that joins the cannabinoid receptors of the body and brain and that have similar effects to …

Indole and indazole synthetic cannabinoids (SCs) featuring l-valinate or l-tert-leucinate
pendant group have recently emerged as prevalent recreational drugs, and their use has …

Synthetic cannabinoid receptor agonists (SCRAs) are an evolving class of new psychoactive
substances (NPS) with structurally diverse compounds emerging each year. Due to the rapid …

Synthetic cannabinoids (SCs) are a chemically diverse group of new psychoactive
substances (NPSs) that target the endocannabinoid system, triggering a plethora of actions …

Synthetic cannabinoids (SCs) are the largest group of compounds currently monitored in
Europe by the EU Early Warning System on new psychoactive substances. Emerging …

Introduction: The emergence of novel psychoactive substances has changed the
epidemiology of drugs used recreationally throughout Europe and have posed significant …