Pathogenesis of gram-negative bacteremia

CL Holmes, MT Anderson, HLT Mobley… - Clinical microbiology …, 2021 - Am Soc Microbiol
Gram-negative bacteremia is a devastating public health threat, with high mortality in
vulnerable populations and significant costs to the global economy. Concerningly, rates of …

Infectious threats, the intestinal barrier, and its trojan horse: dysbiosis

S Iacob, DG Iacob - Frontiers in microbiology, 2019 - frontiersin.org
The ecosystem of the gut microbiota consists of diverse intestinal species with multiple
metabolic and immunologic activities and it is closely connected with the intestinal epithelia …

An Organ System-Based Synopsis of Pseudomonas aeruginosa Virulence

CD Morin, E Déziel, J Gauthier, RC Levesque, GW Lau - Virulence, 2021 - Taylor & Francis
Driven in part by its metabolic versatility, high intrinsic antibiotic resistance, and a large
repertoire of virulence factors, Pseudomonas aeruginosa is expertly adapted to thrive in a …

[HTML][HTML] Pseudomonas aeruginosa: Infections and novel approaches to treatment “Knowing the enemy” the threat of Pseudomonas aeruginosa and exploring novel …

N Sathe, P Beech, L Croft, C Suphioglu, A Kapat… - Infectious Medicine, 2023 - Elsevier
Pseudomonas aeruginosa is an aerobic Gram-negative rod-shaped bacterium with a
comparatively large genome and an impressive genetic capability allowing it to grow in a …

Antibiogram profile and virulence signatures of Pseudomonas aeruginosa isolates recovered from selected agrestic hospital effluents

Q Mapipa, TO Digban, NE Nnolim, UU Nwodo - Scientific Reports, 2021 - nature.com
Hospital wastewater (HWW) harbours diverse microbial species and a miscellany of
genome that would facilitate the emergence of novel pathogen upon genome integration …

Exoproteomics for Better Understanding Pseudomonas aeruginosa Virulence

S Sauvage, J Hardouin - Toxins, 2020 - mdpi.com
Pseudomonas aeruginosa is the most common human opportunistic pathogen associated
with nosocomial diseases. In 2017, the World Health Organization has classified P …

Virulence profiles of some Pseudomonas aeruginosa clinical isolates and their association with the suppression of Candida growth in polymicrobial infections

RM Abd El-Baky, SA Mandour, EF Ahmed, ZS Hashem… - Plos one, 2020 - journals.plos.org
Pseudomonas aeruginosa is an opportunistic pathogen that can cause a variety of diseases
especially in the hospital environment. However, this pathogen also exhibits antimicrobial …

Pseudomonas aeruginosa clinical blood isolates display significant phenotypic variability

RJ Scheffler, BP Bratton, Z Gitai - Plos one, 2022 - journals.plos.org
Pseudomonas aeruginosa is a significant threat in healthcare settings where it deploys a
wide host of virulence factors to cause disease. Many virulence-related phenotypes such as …

Sodium New Houttuyfonate Affects Transcriptome and Virulence Factors of Pseudomonas aeruginosa Controlled by Quorum Sensing

Y Zhao, L Mei, Y Si, J Wu, J Shao, T Wang… - Frontiers in …, 2020 - frontiersin.org
As a major opportunistic pathogen, Pseudomonas aeruginosa can produce various
virulence factors and form biofilms. These processes are controlled by the quorum sensing …

The putative bacterial oxygen sensor Pseudomonas prolyl hydroxylase (PPHD) suppresses antibiotic resistance and pathogenicity in Pseudomonas aeruginosa

B Schaible, B Crifo, K Schaffer, CT Taylor - Journal of Biological Chemistry, 2020 - ASBMB
Pseudomonas aeruginosa is an extracellular opportunistic bacterial pathogen commonly
associated with infectious complications in susceptible individuals, such as those with …