Current use of PSMA–PET in prostate cancer management

T Maurer, M Eiber, M Schwaiger… - Nature Reviews …, 2016 - nature.com
Currently, the findings of imaging procedures used for detection or staging of prostate
cancer depend on morphology of lymph nodes or bone metabolism and do not always meet …

PSMA-targeted radiopharmaceuticals for imaging and therapy

HJ Wester, M Schottelius - Seminars in nuclear medicine, 2019 - Elsevier
As described in more detail in other contributions in this issue of Seminars in Nuclear
Medicine, prostate-specific membrane antigen (PSMA) has become one of the most …

Glu-ureido–based inhibitors of prostate-specific membrane antigen: lessons learned during the development of a novel class of low-molecular-weight theranostic …

K Kopka, M Benešová, C Bařinka… - Journal of Nuclear …, 2017 - Soc Nuclear Med
In recent years, several radioligands targeting prostate-specific membrane antigen (PSMA)
have been clinically introduced as a new class of theranostic radiopharmaceuticals for the …

Glutamate carboxypeptidase II in diagnosis and treatment of neurologic disorders and prostate cancer

C Barinka, C Rojas, B Slusher… - Current medicinal …, 2012 - ingentaconnect.com
Glutamate carboxypeptidase II (GCPII) is a membrane-bound binuclear zinc
metallopeptidase with the highest expression levels found in the nervous and prostatic …

PET imaging in prostate cancer: focus on prostate-specific membrane antigen

RC Mease, CA Foss, MG Pomper - Current topics in medicinal …, 2013 - ingentaconnect.com
Prostate cancer (PCa) is the second leading cause of cancer-related death in American
men. Positron emission tomography/computed tomography (PET/CT) with emerging …

[HTML][HTML] Prostate-specific membrane antigen as a target for cancer imaging and therapy

AP Kiess, SR Banerjee, RC Mease… - The quarterly journal …, 2015 - ncbi.nlm.nih.gov
The prostate-specific membrane antigen (PSMA) is a molecular target whose use has
resulted in some of the most productive work toward imaging and treating prostate cancer …

Targeting prostate cancer: prostate‐specific membrane antigen based diagnosis and therapy

T Wüstemann, U Haberkorn, J Babich… - Medicinal research …, 2019 - Wiley Online Library
The high incidence rates of prostate cancer (PCa) raise demand for improved therapeutic
strategies. Prostate tumors specifically express the prostate‐specific membrane antigen …

Alterations in androgen deprivation enhanced prostate-specific membrane antigen (PSMA) expression in prostate cancer cells as a target for diagnostics and therapy

B Meller, F Bremmer, CO Sahlmann, S Hijazi, C Bouter… - EJNMMI research, 2015 - Springer
Background Prostate-specific membrane antigen (PSMA) is a promising target for
diagnostics and therapy of prostate carcinoma (PCa). Based on the hypothesis that PSMA …

A remote arene-binding site on prostate specific membrane antigen revealed by antibody-recruiting small molecules

AX Zhang, RP Murelli, C Barinka, J Michel… - Journal of the …, 2010 - ACS Publications
Prostate specific membrane antigen (PSMA) is a membrane-bound glutamate
carboxypeptidase overexpressed in many forms of prostate cancer. Our laboratory has …

The therapeutic and diagnostic potential of the prostate specific membrane antigen/glutamate carboxypeptidase II (PSMA/GCPII) in cancer and neurological disease

JC Evans, M Malhotra, JF Cryan… - British journal of …, 2016 - Wiley Online Library
Prostate specific membrane antigen (PSMA) otherwise known as glutamate
carboxypeptidase II (GCPII) is a membrane bound protein that is highly expressed in …