Increasing evidence indicates the involvement of B cells in the pathogenesis of multiple
sclerosis (MS), but their precise roles are unclear. In this Review, we provide an overview of …

Although most autoimmune diseases are considered to be CD4 T cell-or antibody-mediated,
many respond to CD20-depleting antibodies that have limited influence on CD4 and plasma …

Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous
system (CNS) where immunopathology is thought to be mediated by myelin-reactive CD4+ T …

Background Patients treated with anti-CD20 therapy are particularly at risk of developing
severe coronavirus disease 2019 (COVID-19); however, little is known regarding COVID-19 …

Multiple sclerosis (MS) is a chronic neurodegenerative disease characterized by the
progressive loss of axonal myelin in several areas of the central nervous system (CNS) that …

The origin and function of CD20+ T cells are poorly understood. Here, we characterized
CD20+ T cells in mice and humans and investigated how they are affected by anti-CD20 …

The immune system plays a significant role in multiple sclerosis. While MS was historically
thought to be T cell-mediated, multiple pieces of evidence now support the view that B cells …

COVID-19 vaccination is recommended for multiple sclerosis patients. Disease-modifying
therapies can influence the safety and efficacy of COVID-19 vaccines. RNA, DNA, protein …

Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system
(CNS) that is characterised pathologically by demyelination, gliosis, neuro-axonal damage …

Until recently, in the pathogenesis of Multiple Sclerosis (MS), the contribution of B cells has
been largely underestimated, and the disease was considered a T-cell-mediated disorder …