Theranostic signature of tumor-derived exosomes in cancer

S Kumar, R Dhar, LBSS Kumar, GG Shivji, R Jayaraj… - Medical Oncology, 2023 - Springer
Cancer is the most challenging global health crisis. In the recent times, studies on
extracellular vesicles (EVs) are adding a new chapter to cancer research and reports on EVs …

Formation, contents, functions of exosomes and their potential in lung cancer diagnostics and therapeutics

Z Xia, B Qing, W Wang, L Gu, H Chen… - Thoracic Cancer, 2021 - Wiley Online Library
Lung cancer is the leading cause of cancer‐related death worldwide due to diagnosis in the
advanced stage and drug resistance in the subsequent treatments. Development of novel …

Exosomal circRNA RHOT1 promotes breast cancer progression by targeting miR-204-5p/PRMT5 axis

W Jiang, YP Yu, J Ou, Y Li, N Zhu - Cancer Cell International, 2023 - Springer
Abstract Background Circular RNA RHOT1 (circRHOT1) plays crucial roles in tumorigenesis
by competing with microRNAs. It is largely abundant in tumor cell-derived exosomes …

Recent advances of circular RNAs as biomarkers for osteosarcoma

H Wu, S Zheng, Q He, Y Li - International Journal of General …, 2023 - Taylor & Francis
Osteosarcoma is the most common primary malignant bone tumor in young adult, which is
prone to early metastasis and poor prognosis. The current treatment methods need to be …

Exosomes: A potential therapeutic strategy to fight cancer as drug carriers or immune system regulators

A Abedi, MM Moghaddam, R Kachuei… - Biochimica et Biophysica …, 2024 - Elsevier
Exosome-based cancer immunotherapy is advancing quickly on the concept of artificially
activating the immune system to combat cancer. They can mechanistically change the tumor …

Exosomal transfer of miR-195-5p restrains lung adenocarcinoma progression

Y Zhou, G Wang, J Cai, Y Du, H Li, L Duan… - Experimental Cell …, 2023 - Elsevier
Exosome is an important way for tumor cells to communicate with other cells and plays an
important role in tumor progression. Previous studies revealed that miR-195-5p acts as a …

The role of extracellular vesicles from placenta and endometrium in pregnancy: insights from tumor biology

Y Wang, S Cai, X Chen, Q Sun, T Yin, L Diao - Journal of Reproductive …, 2024 - Elsevier
Extracellular vesicles (EVs) are small membrane-bound particles secreted by various cell
types that play a critical role in intercellular communication by packaging and delivering …

Particular exosomal micro-RNAs and gastrointestinal (GI) cancer cells' roles: Current theories

B Almutairy, MS Alzahrani, DS Waggas… - Experimental Cell …, 2024 - Elsevier
A diverse range of gastrointestinal tract disorders are called gastrointestinal (GI)
malignancies. The transformation of normal cells into precursor cells, precursor cells into …

Differential Immunomodulatory Effects of Head and Neck Cancer-Derived Exosomes on B Cells in the Presence of ATP

M Coray, V Göldi, L Schmid, L Benecke… - International journal of …, 2022 - mdpi.com
Head and neck squamous cell carcinoma (HNSCC) is an aggressive malignancy. Tumor-
derived exosomes (TEX) have immunoregulatory properties. Adenosine triphosphate (ATP) …

Exosomes: Key Players for Treatment of Cancer and Their Future Perspectives

R Gupta, J Gupta, S Roy - ASSAY and Drug Development …, 2024 - liebertpub.com
Cancer is one of the leading causes of mortality worldwide. As the population increases,
there is an enriched thrust for screening a newer delivery system for anticancer agents to …