Zinc coordination complexes as anticancer agents

M Pellei, F Del Bello, M Porchia, C Santini - Coordination Chemistry …, 2021 - Elsevier
Zinc, present in all forms of life, is an essential element for humans. It is one of the most
abundant metals in our body. Because of its importance, any malfunctions of its homeostasis …

Anticancer potential of coumarin and its derivatives

N Bhattarai, AA Kumbhar, YR Pokharel… - Mini Reviews in …, 2021 - ingentaconnect.com
Coumarins are found in higher plants like Rutaceae and Umbelliferae and essential oils of
cinnamon bark, cassia leaf, and lavender oil. Coumarin compounds show different …

Synthesis of palladium (II) complexes via Michael addition: antiproliferative effects through ROS-mediated mitochondrial apoptosis and docking with SARS-CoV-2

J Haribabu, S Srividya, D Mahendiran… - Inorganic …, 2020 - ACS Publications
Metal complexes have numerous applications in the current era, particularly in the field of
pharmaceutical chemistry and catalysis. A novel synthetic approach for the same is always a …

Coordination compounds of pyrazolone‐based ligand: Design, characterization, biological evaluation, antitumor efficiency, and DNA binding evaluation supported by …

SA Ibrahim, A Ragab… - Applied Organometallic …, 2022 - Wiley Online Library
Abstract Cu (II), Ni (II), Mn (II), and Cr (III) chelates of the organic ligand named 3‐(furan‐2‐
yl)‐5‐oxo‐N, 1‐diphenyl‐4, 5‐dihydro‐1H‐pyrazole‐4‐carbothioamide ligand (abbreviated …

[HTML][HTML] Advances in thiosemicarbazone metal complexes as anti-lung cancer agents

XG Bai, Y Zheng, J Qi - Frontiers in Pharmacology, 2022 - frontiersin.org
The great success of cisplatin as a chemotherapeutic agent considerably increased
research efforts in inorganic biochemistry to identify more metallic drugs having the potential …

Various coordination modes of new coumarin Schiff bases toward Cobalt (III) ion: synthesis, spectral characterization, in vitro cytotoxic activity, and investigation of …

K Giriraj, MS Mohamed Kasim… - Applied …, 2022 - Wiley Online Library
Four Co (III) complexes containing substituted acetyl coumarin Schiff bases have been
synthesized and structurally characterized using IR, UV–visible, 1H nuclear magnetic …

Recent developments on the potential biological applications of transition metal complexes of thiosemicarbazone derivatives

V Singh, VNV Palakkeezhillam, V Manakkadan… - Polyhedron, 2023 - Elsevier
This review talks about the synthesis, and coordination chemistry of thiosemicarbazone and
its bonding with transition metals like copper, nickel, zinc, palladium, and ruthenium and …

Polynuclear zinc (II) complexes of thiosemicarbazone: Synthesis, X-ray structure and biological evaluation

M Mohanty, A Banerjee, S Biswal, A Horn Jr… - Journal of Inorganic …, 2020 - Elsevier
Two new dimeric Zn (II)([{ZnL 1 (DMSO 2)} 2]· DMSO (1),[{ZnL 2 Cl} 2](2)) and a novel
tetrameric Zn (II) complex ([(Zn 2 L 3) 2 (μ–OAc) 2 (μ 3–O) 2](3)), where H 2 L 1= 4–(p …

[HTML][HTML] Latest developments in coumarin-based anticancer agents: mechanism of action and structure–activity relationship studies

M Koley, J Han, VA Soloshonok… - RSC Medicinal …, 2024 - ncbi.nlm.nih.gov
Many researchers around the world are working on the development of novel anticancer
drugs with different mechanisms of action. In this case, coumarin is a highly promising …

N-substitution in isatin thiosemicarbazones decides nuclearity of Cu (II) complexes–Spectroscopic, molecular docking and cytotoxic studies

J Haribabu, OI Alajrawy, K Jeyalakshmi… - … Acta Part A: Molecular …, 2021 - Elsevier
Abstract The mono-(1) and bi-nuclear (2) copper (II) complexes containing N-substituted
isatin thiosemicarbazone (s) were synthesized, and characterized by analytical and …