The mechanisms of multidrug resistance of breast cancer and research progress on related reversal agents

S Yu, J Zheng, Y Zhang, D Meng, Y Wang, X Xu… - Bioorganic & Medicinal …, 2023 - Elsevier
Chemotherapy is the mainstay in the treatment of breast cancer. However, many drugs that
are commonly used in clinical practice have a high incidence of side effects and multidrug …

Oestrogen receptor-independent actions of oestrogen in cancer

P Gopinath, RP Oviya, G Gopisetty - Molecular Biology Reports, 2023 - Springer
Oestrogen, the primary female sex hormone, plays a significant role in tumourigenesis. The
major pathway for oestrogen is via binding to its receptor [oestrogen receptor (ERα or β)] …

Design, synthesis, and in‐silico study of novel triarylethylene analogs with dual anti‐estrogenic and serotonergic activity

T Mostafa, M Albeir, J Wober, A Abadi… - Drug Development …, 2024 - Wiley Online Library
Estrogen receptor is an important target in breast cancer. Serotonin receptors (5‐HT2A and
5‐HT2C, in particular) were investigated for a potential role in development and progression …

[HTML][HTML] Prognostic role of serum soluble ST2 of advanced breast cancer patients: a retrospective cohort study

C Chen, J Li, L Rossi, P Sun, T She… - Translational Cancer …, 2023 - ncbi.nlm.nih.gov
Background The soluble suppression of tumorigenicity 2 receptor (sST2) binds to interleukin-
33 (IL-33) and blocks IL-33 and ST2 binding, suggesting that sST2 acts as a “decoy” …