Current antiplatelet treatment strategy in patients with diabetes mellitus

JH Jung, US Tantry, PA Gurbel… - Diabetes & metabolism …, 2015 - synapse.koreamed.org
Patients with diabetes mellitus (DM) have accelerated atherosclerosis with an increased risk
for atherothrombotic cardiovascular complications. A state of high platelet reactivity and …

[HTML][HTML] Anti-platelet drugs and their necessary interaction with endothelial mediators and platelet cyclic nucleotides for therapeutic efficacy

RB Knowles, TD Warner - Pharmacology & therapeutics, 2019 - Elsevier
For many millions of patients at secondary risk of coronary thrombosis pharmaceutical
protection is supplied by dual anti-platelet therapy. Despite substantial therapeutic …

Effectiveness and safety of high dose clopidogrel plus aspirin in ischemic stroke patients with the single CYP2C19 loss-of-function allele: a randomized trial

H Wu, H Song, L Dou, B Gao, Y Pan, M Dong, Q Chen… - BMC neurology, 2020 - Springer
Background Dual antiplatelet aggregation therapy leads to better outcomes in patients with
carotid artery stenosis, intracranial artery stenosis, minor strokes, or transient ischaemic …

The dipyridamole added to dual antiplatelet therapy in cerebral infarction after first acute myocardial infarction: a nationwide, case-control study

MT Wang, CK Tsai, SH Kuo, WC Huang, KC Lin… - Frontiers in …, 2018 - frontiersin.org
Background and Purpose: No previous study has compared the impact of dipyridamole-
based triple antiplatelet therapy on secondary stroke prevention and long-term outcomes to …

Influence of rabeprazole and famotidine on pharmacodynamic profile of dual antiplatelet therapy in clopidogrel-sensitive patients: The randomized, prospective …

JH Ahn, Y Park, JS Bae, JY Jang, KH Kim, MG Kang… - Platelets, 2020 - Taylor & Francis
Although acid suppressants are needed to attenuate gastrointestinal bleeding (GIB) after
percutaneous coronary intervention (PCI), pharmacodynamic interaction between …

O πολυμορφισμός του κυτοχρώματος P450 CYP2C19 και αντίσταση στη κλοπιδογρέλη

Ν Μιχαηλίδης - repo.lib.duth.gr
3.3. 4.2. ABCB1 20 3.3. 5. Θεραπευτικές θεωρήσεις αντιαιµοπεταλιακών φαρμάκων 20 3.3. 6.
Αλληλεπιδράσεις με άλλα φάρμακα: Αναστολείς αντλίας πρωτονίων 21 3.4. Έμφραγμα του …

Dipyridamole and PDE inhibitors

P Gresele, S Momi, E Falcinelli - Platelets in Thrombotic and Non …, 2017 - Springer
Inhibition of platelet aggregation can be achieved either by the blockade of membrane
receptors or by interaction with intracellular signaling pathways. Cyclic adenosine 3′, 5 …

Interactions between the endothelial mediator's nitric oxide and prostacyclin, and platelet P2Y12 receptor blockade

R Knowles - 2019 - qmro.qmul.ac.uk
An often explored hypothesis is that in at risk patients the chances of experiencing a
thrombotic event is associated with the level of P2Y12 platelet blockade. However, studies …

[PDF][PDF] Monitoring and optimizing antiplatelet therapy in patients undergoing percutaneous coronary intervention

S Leé - 2016 - repo.lib.semmelweis.hu
Az elmúlt néhány évtizedben a perkután koronária intervenció (PCI) kulcsfontosságú
terápiás eszközzé vált a kardiovaszkuláris megbetegedések kezelésében. A beavatkozás …

[引用][C] Aspirin and plavix for stroke ucla CHMP recommends approval of Plavix®(clopidogrel) with aspirin in adults for certain types of strokes

H Rearden