Helminths are extraordinarily successful parasites due to their ability to modulate the host
immune response. They have evolved a spectrum of immunomodulatory molecules that are …

Schistosomiasis is a major cause of morbidity in humans invoked by chronic infection with
parasitic trematodes of the genus Schistosoma. Schistosomes have a complex life-cycle …

Schistosomes are long lived, intravascular parasitic platyhelminths that infect> 200 million
people globally. The molecular mechanisms used by these blood flukes to dampen host …

Infection with Schistosoma haematobium leads to urogenital schistosomiasis, which has
been correlated with the occurrence of bladder cancer. However, mechanisms responsible …

Urogenital schistosomiasis is caused by the blood fluke Schistosoma haematobium and is
one of the most neglected tropical diseases worldwide, afflicting> 100 million people. It is …

Parasitic worms (helminths) developed various immunoregulatory mechanisms to
counteract the immune system of their host. The increasing identification and …

Schistosomiasis is one of the most prominent parasite-induced infectious diseases, causing
tremendous medical and socioeconomic problems. Current studies have reported on the …

Morbidity associated with hepatic and urogenital schistosomiasis stems primarily from the
host immune response directed against schistosome eggs. When eggs become entrapped …

Clinical data have provided evidence that schistosomiasis can promote hepatocellular
carcinogenesis. c‐Jun and STAT3 are critical regulators of liver cancer development and …

Background Schistosomiasis is a neglected disease affecting hundreds of millions
worldwide. Of the three main species affecting humans, Schistosoma haematobium is the …