The role of BST‐2/Tetherin in host protection and disease manifestation

WD Mahauad‐Fernandez… - … inflammation and disease, 2016 - Wiley Online Library
Host cells respond to viral infections by activating immune response genes that are not only
involved in inflammation, but may also predispose cells to cancerous transformation. One …

Single-Cell RNA sequencing reveals unique alterations in the immune panorama and treg subpopulations in mice during the late stages of echinococcus granulosus …

J Wu, J Xiao, M Bai, C Shi, Y Xin, W Zhao… - Infection and …, 2023 - Am Soc Microbiol
Cystic echinococcosis (CE) is a common zoonotic parasitic disease that seriously impacts
public health. However, the full spectrum of immune cell changes in Echinococcus …

Transposable elements regulate thymus development and function

JD Larouche, CM Laumont, A Trofimov, K Vincent… - Elife, 2024 - elifesciences.org
Transposable elements (TEs) are repetitive sequences representing~ 45% of the human
and mouse genomes and are highly expressed by medullary thymic epithelial cells …

Single-cell transcriptomics reveals discrete steps in regulatory T cell development in the human thymus

F Morgana, R Opstelten, MC Slot, AM Scott… - The Journal of …, 2022 - journals.aai.org
Abstract CD4+ CD25+ FOXP3+ regulatory T (Treg) cells control immunological tolerance.
Treg cells are generated in the thymus (tTreg) or in the periphery. Their superior lineage …

Bulk T‐cell receptor sequencing confirms clonality in pediatric eosinophilic esophagitis and identifies a food‐specific repertoire

R Janarthanam, FL Kuang, A Zalewski, K Amsden… - Allergy, 2023 - Wiley Online Library
Abstract Background Eosinophilic esophagitis (EoE) involves a chronic immune‐mediated
response to dietary antigens. Recent work identifies T‐cell clonality in children with EoE …

Transposable elements regulate thymus development and function

L Jean-David, CM Laumont, T Assya, V Krystel… - eLife, 2024 - search.proquest.com
Transposable elements (TEs) are repetitive sequences representing~ 45% of the human
and mouse genomes and are highly expressed by medullary thymic epithelial cells …

Dynamic changes in the regulatory T-cell heterogeneity and function by murine IL-2 mutein

DR Lu, H Wu, I Driver, S Ingersoll, S Sohn… - Life science …, 2020 - life-science-alliance.org
The therapeutic expansion of Foxp3+ regulatory T cells (Tregs) shows promise for treating
autoimmune and inflammatory disorders. Yet, how this treatment affects the heterogeneity …

Activation of the ILT7 receptor and plasmacytoid dendritic cell responses are governed by structurally-distinct BST2 determinants

MG Bego, N Miguet, A Laliberté, N Aschman… - Journal of Biological …, 2019 - ASBMB
Type I interferons (IFN-I) are key innate immune effectors predominantly produced by
activated plasmacytoid dendritic cells (pDCs). By modulating immune responses at their …

Generation and initial characterization of in vivo knockout of tetherin/BST2 in chicken

L Ungrova, P Trefil, J Plachy, J Mucksova, J Kalina… - bioRxiv, 2024 - biorxiv.org
Tetherin/BST2 is an antiviral restriction factor initially described in mammals. It is active
against multiple enveloped viruses at the budding phase, where it is able to physically link …

Tolérance au soi: rôle des éléments transposables dans les tissus somatiques et le thymus

JD Larouche - 2024 - papyrus.bib.umontreal.ca
Les éléments transposables (TE) sont des séquences répétitives représentant environ 45%
des génomes humain et murin. Il est généralement assumé que leur expression est …