BackgroundIt is unclear what the prevalence of metabolic syndrome (MetS) in drug-naïve
first-episode of psychosis (FEP) is, as previous meta-analyses were conducted in minimally …

Objectives To (1) explore trends of risk of bias (ROB) in prediction research over time
following key methodological publications, using the Prediction model Risk Of Bias …

Background Young people with psychosis are at high risk of developing cardiometabolic
disorders; however, there is no suitable cardiometabolic risk prediction algorithm for this …

Around a quarter of people who experience a first episode of psychosis (FEP) will develop
treatment-resistant schizophrenia, but there are currently no established clinically useful …

Background Few investigations have been carried out on metabolic syndrome in
antipsychotic-naïve patients with schizophrenia. Methods Our primary objective was to …

Background Patients with a mental illness are more likely to develop, and die from,
cardiovascular diseases (CVD), necessitating optimal CVD-risk (CVR)-assessment to …

Introduction People with psychosis spectrum disorders (PSD) face an elevated risk of
metabolic syndrome (MetS), which may reduce their life expectancy by nearly 20 …

Background Cardiometabolic dysfunction is common in young people with psychosis.
Recently, the Psychosis Metabolic Risk Calculator (PsyMetRiC) was developed and …

The level of CVD comorbidity remains high in SMDs, indicating that most people with SMDs
have not benefitted from recent medical advances. A complex interplay between genetic and …

Background Latest studies in patients with first episode psychosis (FEP) have shown
alterations in cardiovascular, immune and endocrinological systems. These findings could …