Regulation of eukaryotic gene expression involves a dynamic interplay between the core
transcriptional machinery, transcription factors, and chromatin organization and modification …

Transcription of tRNA genes by RNA polymerase III (RNAPIII) is tuned by signaling
cascades. The emerging notion of differential tRNA gene regulation implies the existence of …

Metazoan organisms have many tRNA genes responsible for decoding amino acids. The set
of all tRNA genes can be grouped in sets of common amino acids and isoacceptor tRNAs …

An adaptive feature of malaria-causing parasites is the digestion of host hemoglobin (HB) to
acquire amino acids (AAs). Here, we describe a link between nutrient availability and …

Background Many environmental factors are associated with GC content evolution.
However, the relationship between GC content and halophilicity has been poorly explored …

The conserved nucleic acid binding protein Translin contributes to numerous facets of
mammalian biology and genetic diseases. It was first identified as a binder of cancer …

Transcription of tRNA genes by RNA Polymerase III (RNAPIII) is tightly regulated by
signaling cascades in response to nutrient availability. The emerging notion of differential …

Plasmodium falciparum has an AT-rich genome with highly biased codon and amino acid
usage that is not balanced by the tRNA genes repertoire. To determine whether individual …

Abstract tRNAs are a driving force of genome evolution in Yeast and Bacteria. Their
deregulation is frequently observed in tumors with Serine tRNAs being often overexpressed …

Saccharomyces cerevisiae is widely used as a model organism for eukaryotic cells and
generally prefers fermentation rather than respiration even under an aerobic environment …