Past, present and future role of retinal imaging in neurodegenerative disease

AH Kashani, S Asanad, JW Chan, MB Singer… - Progress in retinal and …, 2021 - Elsevier
Retinal imaging technology is rapidly advancing and can provide ever-increasing amounts
of information about the structure, function and molecular composition of retinal tissue in …

Retinal imaging biomarkers of Alzheimer's disease: A systematic review and meta‐analysis of studies using brain amyloid beta status for case definition

G Ashraf, M McGuinness, MA Khan… - Alzheimer's & …, 2023 - Wiley Online Library
Introduction We performed a systematic review and meta‐analysis of the association
between retinal imaging parameters and Alzheimer's disease (AD). Methods PubMed …

Gardenia jasminoides J. Ellis extract alleviated white matter damage through promoting the differentiation of oligodendrocyte precursor cells via suppressing …

C Zang, H Liu, C Ju, F Yuan, J Ning, M Shang, X Bao… - Food & Function, 2022 - pubs.rsc.org
Increasing evidence has highlighted the role of white matter damage in the pathology of
Alzheimer's disease (AD). Previous research has shown that a mixture of crocin analogues …

Thinner inner retinal layers are associated with lower cognitive performance, lower brain volume, and altered white matter network structure—The Maastricht Study

FCT van der Heide, ILM Steens, B Limmen… - Alzheimer's & …, 2024 - Wiley Online Library
INTRODUCTION The retina may provide non‐invasive, scalable biomarkers for monitoring
cerebral neurodegeneration. METHODS We used cross‐sectional data from The Maastricht …

The Retinal Inner Plexiform Synaptic Layer Mirrors Grey Matter Thickness of Primary Visual Cortex with Increased Amyloid β Load in Early Alzheimer's Disease

L Jorge, N Canário, R Martins, B Santiago… - Neural …, 2020 - Wiley Online Library
The retina may serve as putative window into neuropathology of synaptic loss in Alzheimer's
disease (AD). Here, we investigated synapse‐rich layers versus layers composed by …

Investigating the spatial associations between amyloid-β deposition, grey matter volume, and neuroinflammation in Alzheimer's disease

L Jorge, R Martins, N Canário, C Xavier… - Journal of …, 2021 - content.iospress.com
Background: It has been proposed that amyloid-β (Aβ) plays a causal role in Alzheimer's
disease (AD) by triggering a series of pathologic events—possibly including …

Applying Retinal Vascular Structures Characteristics Coupling with Cortical Visual System in Alzheimer's Disease Spectrum Patients

L Wang, Z Hu, H Chen, X Sheng, R Qin, P Shao… - Brain Sciences, 2023 - mdpi.com
Cortical visual system dysfunction is closely related to the progression of Alzheimer's
Disease (AD), while retinal vascular structures play an important role in the integrity of the …

Correlation between retinal structure and brain multimodal magnetic resonance imaging in patients with Alzheimer's disease

X Hao, W Zhang, B Jiao, Q Yang, X Zhang… - Frontiers in Aging …, 2023 - frontiersin.org
Background The retina imaging and brain magnetic resonance imaging (MRI) can both
reflect early changes in Alzheimer's disease (AD) and may serve as potential biomarker for …

Intravoxel incoherent motion diffusion-weighted imaging in the characterization of Alzheimer's disease

N Xia, Y Li, Y Xue, W Li, Z Zhang, C Wen, J Li… - Brain Imaging and …, 2022 - Springer
Objectives Alzheimer's disease (AD) is the most common type of dementia, and
characterizing brain changes in AD is important for clinical diagnosis and prognosis. This …

When Sex Matters: Differences in the Central Nervous System as Imaged by OCT through the Retina

A Nunes, P Serranho, P Guimarães, J Ferreira… - Journal of …, 2023 - mdpi.com
Background: Retinal texture has gained momentum as a source of biomarkers of
neurodegeneration, as it is sensitive to subtle differences in the central nervous system from …