In this last decade, our understanding of the complex factors and processes that drive
cancer development and progression has broadened in scope and grown in depth. Today, it …

The development of multi-functional Pt (IV) complexes as chemotherapeutic agents has
gained growing attention in medical oncology. However, the design of multi-functional tumor …

Complexes that incorporate both ligand (s) and metal (s) exhibiting cytotoxic activity can
especially be interesting to develop multifunctional drug molecules with desired activities. In …

Most of the currently available cytotoxic agents for tackling cancer are devoid of selectivity,
thus causing severe side-effects. This situation stimulated us to develop new antiproliferative …

We have synthesized a series of novel substituted sulfonyl ethylenediamine (en) RuII arene
complexes 1–8 of [(η6-arene) Ru (R1-SO2-EnBz) X], where the arene is benzene, HO (CH2) …

The aim of this study was to determine the reactivity and stability properties of a novel series
of tricarbonylrhenium (I) complexes with 1, 2, 3-triazole-pyridine based on monovalent and …

Carcinogenesis cannot be explained only by genetic alterations. Epigenetic processes such
as histone modification via (de) acetylation play a key role in gene expression, where …

To study the relationship between the [2+ 2] photocycloaddition reactivities of 1, 4-
cyclohexadiene derivatives (1, 4− CHDs) and their structures, photophysical properties of a …