Old and new perspectives in the management of high-risk, locally advanced or recurrent, and metastatic vulvar cancer

A Gadducci, L Cionini, A Romanini, A Fanucchi… - Critical reviews in …, 2006 - Elsevier
During the last decades there has been a continuing evolution in the surgical approach of
squamous cell carcinoma of the vulva that has been traditionally treated with radical …

Chemoradiation for advanced primary vulval cancer

TS Shylasree, A Bryant… - Cochrane Database of …, 2011 - cochranelibrary.com
Background Vulval cancer is a rare gynaecological cancer. There is no standard approach
for treating locally advanced primary vulval cancer (FIGO stage III and IV). Combined …

Intensity-modulated radiotherapy for the treatment of vulvar carcinoma: a comparative dosimetric study with early clinical outcome

S Beriwal, DE Heron, H Kim, G King, J Shogan… - International Journal of …, 2006 - Elsevier
Objectives: To assess early clinical outcome of intensity-modulated radiation therapy (IMRT)
in the treatment of vulvar cancer and compare dosimetric parameters with 3D conformal …

Vulvar carcinoma: Standard of care and perspectives

C Chargari, J Wasserman, A Gabro… - Journal of Clinical …, 2024 - ascopubs.org
PURPOSE Treatment of vulvar carcinoma (VC) is challenging. The objectives of this review
were to describe for clinicians the epidemiologic and clinical aspects of VC, the standard of …

Local and regional recurrence of vulval cancer: management dilemmas

J Coulter, N Gleeson - Best practice & research Clinical obstetrics & …, 2003 - Elsevier
Vulval cancer has an incidence of 1–2/100 000. Approximately one-third of patients develop
recurrent disease usually within the first 2 years following primary treatment. Isolated vulval …

Preoperative chemoradiation for locally advanced carcinoma of the vulva

K Gerszten, RN Selvaraj, J Kelley, C Faul - Gynecologic oncology, 2005 - Elsevier
OBJECTIVE.: A twice daily (BID) radiation treatment schedule (interval of 4–6 h) delivered
concurrent with chemotherapy for advanced or critically located carcinoma of the vulva was …

Multimodality imaging of vulvar cancer: staging, therapeutic response, and complications

C Viswanathan, K Kirschner, M Truong… - American Journal of …, 2013 - Am Roentgen Ray Soc
OBJECTIVE. Vulvar carcinoma is a rare malignancy, most commonly seen in elderly women.
Survival depends on the lymph node status. Lymph node–negative patients have a 5-year …

Systemic therapy in squamous cell carcinoma of the vulva: current status and future directions

CJ Reade, LR Eiriksson, H Mackay - Gynecologic Oncology, 2014 - Elsevier
Objective The advances achieved in the surgical management of vulvar squamous cell
carcinoma (SCC) have not been mirrored in systemic therapy options. The objective of this …

Locally advanced vulva cancer: A single centre review of anovulvectomy and a systematic review of surgical, chemotherapy and radiotherapy alternatives. Is an …

RL O'Donnell, L Verleye, N Ratnavelu, K Galaal… - Gynecologic …, 2017 - Elsevier
Introduction Treatment of locally advanced vulva cancer (LAVC) remains challenging. Due
to the lack of randomised trials many questions regarding the indications for different …

Chemoradiation with 5-fluorouracil and mitomycin C in the treatment of vulvar squamous cell carcinoma

N Mulayim, DF Silver, PE Schwartz, S Higgins - Gynecologic oncology, 2004 - Elsevier
Objective. To investigate the acute and late toxicities associated with the use of
chemoradiation therapy (CRT) with 5-fluorouracil (5-FU) and mitomycin C or mitomycin C …