Structural parameters of nanoparticles affecting their toxicity for biomedical applications: a review

R Abbasi, G Shineh, M Mobaraki, S Doughty… - Journal of Nanoparticle …, 2023 - Springer
Rapidly growing interest in using nanoparticles (NPs) for biomedical applications has
increased concerns about their safety and toxicity. In comparison with bulk materials, NPs …

Cancer stem cells—origins and biomarkers: perspectives for targeted personalized therapies

L Walcher, AK Kistenmacher, H Suo, R Kitte… - Frontiers in …, 2020 - frontiersin.org
The use of biomarkers in diagnosis, therapy and prognosis has gained increasing interest
over the last decades. In particular, the analysis of biomarkers in cancer patients within the …

Nanomaterial-based blood-brain-barrier (BBB) crossing strategies

J Xie, Z Shen, Y Anraku, K Kataoka, X Chen - Biomaterials, 2019 - Elsevier
Increasing attention has been paid to the diseases of central nervous system (CNS). The
penetration efficiency of most CNS drugs into the brain parenchyma is rather limited due to …

Tumor microenvironment-responsive intelligent nanoplatforms for cancer theranostics

F Gong, N Yang, X Wang, Q Zhao, Q Chen, Z Liu… - Nano Today, 2020 - Elsevier
The design and development of tumor microenvironment (TME)-responsive intelligent
nanoplatforms have attracted increasing interest to enhance the therapeutic effects of drugs …

Enzyme responsive drug delivery systems in cancer treatment

M Shahriari, M Zahiri, K Abnous, SM Taghdisi… - Journal of Controlled …, 2019 - Elsevier
Recent technological approaches in drug delivery have attracted scientist interest for
improving therapeutic index of medicines and drug compliance. One of the powerful …

Targeted doxorubicin-loaded mesenchymal stem cells-derived exosomes as a versatile platform for fighting against colorectal cancer

E Bagheri, K Abnous, SA Farzad, SM Taghdisi… - Life sciences, 2020 - Elsevier
Exosomes hold great potential for cancer treatment to deliver therapeutics due to its inherent
low immunogenicity. Exosomes are biocompatible cell-exocytosed secreted vesicles by …

[HTML][HTML] Applications of nanotechnology in drug delivery to the central nervous system

M Saeedi, M Eslamifar, K Khezri, SM Dizaj - Biomedicine & …, 2019 - Elsevier
In recent years, the researchers and drug designers have given growing attention to new
nanotechnology strategies to improve drug delivery to the central nervous system (CNS) …

Recent advances in polymeric micelles for anti-cancer drug delivery

S Biswas, P Kumari, PM Lakhani, B Ghosh - European Journal of …, 2016 - Elsevier
Block co-polymeric micelles receive increased attention due to their ability to load
therapeutics, deliver the cargo to the site of action, improve the pharmacokinetic of the …

Aptamer-functionalized nanoparticles in targeted delivery and cancer therapy

Z Fu, J Xiang - International Journal of Molecular Sciences, 2020 - mdpi.com
Using nanoparticles to carry and delivery anticancer drugs holds much promise in cancer
therapy, but nanoparticles per se are lacking specificity. Active targeting, that is, using …

Drug-loaded PEG-PLGA nanoparticles for cancer treatment

D Zhang, L Liu, J Wang, H Zhang, Z Zhang… - Frontiers in …, 2022 - frontiersin.org
Nanoparticles based on single-component synthetic polymers, such as poly (lactic acid-co-
glycolic acid)(PLGA), have been extensively studied for antitumor drug delivery and …