Glycan-specific molecularly imprinted polymers towards cancer diagnostics: merits, applications, and future perspectives

P Li, Z Liu - Chemical Society Reviews, 2024 - pubs.rsc.org
Aberrant glycans are a hallmark of cancer states. Notably, emerging evidence has
demonstrated that the diagnosis of cancers with tumour-specific glycan patterns holds great …

Lectins: tools for the molecular understanding of the glycocode

M Ambrosi, NR Cameron, BG Davis - Organic & biomolecular …, 2005 - pubs.rsc.org
Recent progress in glycobiology has revealed that cell surface oligosaccharides play an
essential role in recognition events. More precisely, these saccharides may be complexed …

Carbohydrate recognition by boronolectins, small molecules, and lectins

S Jin, Y Cheng, S Reid, M Li… - Medicinal research …, 2010 - Wiley Online Library
Carbohydrates are known to mediate a large number of biological and pathological events.
Small and macromolecules capable of carbohydrate recognition have great potentials as …

Structural and thermodynamic analyses of solute-binding protein from Bifidobacterium longum specific for core 1 disaccharide and lacto-N-biose I

R Suzuki, J Wada, T Katayama, S Fushinobu… - Journal of Biological …, 2008 - ASBMB
Recently, a gene cluster involving a phosphorylase specific for lacto-N-biose I (LNB; Galβ1–
3GlcNAc) and galacto-N-biose (GNB; Galβ1–3GalNAc) has been found in Bifidobacterium …

The antineoplastic lectin of the common edible mushroom (Agaricus bisporus) has two binding sites, each specific for a different configuration at a single epimeric …

ME Carrizo, S Capaldi, M Perduca, FJ Irazoqui… - Journal of Biological …, 2005 - ASBMB
The lectin from the common mushroom Agaricus bisporus, the most popular edible species
in Western countries, has potent antiproliferative effects on human epithelial cancer cells …

Strategies and tactics for the development of selective glycan-binding proteins

EM Ward, ME Kizer, B Imperiali - ACS chemical biology, 2021 - ACS Publications
The influences of glycans impact all biological processes, disease states, and pathogenic
interactions. Glycan-binding proteins (GBPs), such as lectins, are decisive tools for …

Lectin engineering, a molecular evolutionary approach to expanding the lectin utilities

D Hu, H Tateno, J Hirabayashi - Molecules, 2015 - mdpi.com
In the post genomic era, glycomics—the systematic study of all glycan structures of a given
cell or organism—has emerged as an indispensable technology in various fields of biology …

Survey of the year 2001 commercial optical biosensor literature

RL Rich, DG Myszka - Journal of Molecular Recognition, 2002 - Wiley Online Library
We have assembled references of 700 articles published in 2001 that describe work
performed using commercially available optical biosensors. To illustrate the technology's …

Glyco-biosensors: Recent advances and applications for the detection of free and bound carbohydrates

S Cunningham, JQ Gerlach, M Kane, L Joshi - Analyst, 2010 - pubs.rsc.org
The field of biosensor development now encompasses several areas specifically geared
toward the rapid and sensitive detection, identification, and quantification of target analytes …

Computationally guided conversion of the specificity of E-selectin to mimic that of Siglec-8

X Wang, MS Hanes, RD Cummings… - Proceedings of the …, 2022 - National Acad Sciences
Sulfated glycans have been found to be associated with various diseases and therefore
have significant potential in molecular pathology as biomarkers. Although lectins are useful …