COVID-19 vaccines for patients with cancer: benefits likely outweigh risks

JK Hwang, T Zhang, AZ Wang, Z Li - Journal of hematology & oncology, 2021 - Springer
Less than a year since the start of the COVID-19 pandemic, ten vaccines against SARS-CoV-
2 have been approved for at least limited use, with over sixty others in clinical trials. This …

Infections associated with immunotherapeutic and molecular targeted agents in hematology and oncology. A position paper by the European Conference on Infections …

G Maschmeyer, J De Greef, SC Mellinghoff, A Nosari… - Leukemia, 2019 - nature.com
A multitude of new agents for the treatment of hematologic malignancies has been
introduced over the past decade. Hematologists, infectious disease specialists, stem cell …

Efficacy of the BNT162b2 mRNA COVID-19 vaccine in patients with chronic lymphocytic leukemia

Y Herishanu, I Avivi, A Aharon, G Shefer… - Blood, The Journal …, 2021 - ashpublications.org
Patients with chronic lymphocytic leukemia (CLL) have an increased risk for severe COVID-
19 disease and mortality. The goal of this study was to determine the efficacy of COVID-19 …

COVID-19 vaccine efficacy in patients with chronic lymphocytic leukemia

LE Roeker, DA Knorr, MC Thompson, M Nivar… - Leukemia, 2021 - nature.com
Methods We examined 44 consecutive patients with CLL who received two doses of mRNA
vaccine (BNT162b2 or mRNA-1273) between 1/2/21 and 3/12/21 and were tested for anti …

Antibody responses after first and second Covid-19 vaccination in patients with chronic lymphocytic leukaemia

H Parry, G McIlroy, R Bruton, M Ali, C Stephens… - Blood cancer …, 2021 - nature.com
B-cell chronic lymphocytic leukaemia (CLL) is associated with immunosuppression and
patients are at increased clinical risk following SARS-CoV-2 infection. Covid-19 vaccines …

Effect of Bruton tyrosine kinase inhibitor on efficacy of adjuvanted recombinant hepatitis B and zoster vaccines

C Pleyer, MA Ali, JI Cohen, X Tian… - Blood, The Journal …, 2021 - ashpublications.org
Vaccinations are effective in preventing infections; however, it is unknown if patients with
chronic lymphocytic leukemia (CLL) who are treatment naïve (TN) or receiving Bruton …

Infectious complications of biological and small molecule targeted immunomodulatory therapies

JS Davis, D Ferreira, E Paige, C Gedye… - Clinical microbiology …, 2020 - Am Soc Microbiol
The past 2 decades have seen a revolution in our approach to therapeutic
immunosuppression. We have moved from relying on broadly active traditional medications …

Vaccination of patients with haematological malignancies who did not have transplantations: guidelines from the 2017 European Conference on Infections in …

M Mikulska, S Cesaro, H de Lavallade… - The Lancet Infectious …, 2019 - thelancet.com
Patients with haematological malignancies are at high risk of infection because of various
mechanisms of humoral and cell-mediated immune deficiencies, which mainly depend on …

BTK inhibitors in chronic lymphocytic leukemia: biological activity and immune effects

M Palma, TA Mulder, A Österborg - Frontiers in immunology, 2021 - frontiersin.org
Bruton´ s tyrosine kinase (BTK) inhibitor (BTKi) s block the B-cell receptor (BCR) signaling
cascade by binding to the BTK enzyme preventing the proliferation and survival of malignant …

Poor neutralizing antibody responses in 106 patients with WM after vaccination against SARS-CoV-2: a prospective study

M Gavriatopoulou, E Terpos… - Blood …, 2021 - ashpublications.org
Immunocompromised patients with hematologic malignancies are more susceptible to
COVID-19 and at higher risk of severe complications and worse outcomes compared with …