AZD1222-induced nasal antibody responses are shaped by prior SARS-CoV-2 infection and correlate with virologic outcomes in breakthrough infection
AA Aksyuk, H Bansal, D Wilkins, AM Stanley… - Cell Reports …, 2023 - cell.com
The nasal mucosa is an important initial site of host defense against severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) infection. However, intramuscularly administered …
syndrome coronavirus 2 (SARS-CoV-2) infection. However, intramuscularly administered …
2022 White Paper on Recent Issues in Bioanalysis: ICH M10 BMV Guideline & Global Harmonization; Hybrid Assays; Oligonucleotides & ADC; Non-Liquid & Rare …
M Szapacs, W Jian, D Spellman, J Cunliffe… - Bioanalysis, 2023 - Taylor & Francis
Abstract The 16th Workshop on Recent Issues in Bioanalysis (16th WRIB) took place in
Atlanta, GA, USA on September 26–30, 2022. Over 1000 professionals representing …
Atlanta, GA, USA on September 26–30, 2022. Over 1000 professionals representing …
Detailed Structural Elucidation of Antibody-Drug Conjugate Biotransformation Species Using High Resolution Multiple Reaction Monitoring Mass Spectrometry with …
Antibody-drug conjugates (ADCs) are a promising drug modality substantially expanding in
both the discovery space and clinical development. Assessing the biotransformation of …
both the discovery space and clinical development. Assessing the biotransformation of …
Accelerating therapeutics development during a pandemic: population pharmacokinetics of the long-acting antibody combination AZD7442 (tixagevimab/cilgavimab) …
ABSTRACT AZD7442 is a combination of severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2)-neutralizing antibodies, tixagevimab and cilgavimab, developed for pre …
(SARS-CoV-2)-neutralizing antibodies, tixagevimab and cilgavimab, developed for pre …
Bioanalytical method development for monoclonal antibodies: advances and challenges
SDM Kallam, A Bodapati, AS Reddy… - Cellular, Molecular and …, 2025 - cmbr-journal.com
Monoclonal antibodies (mAbs) represent a cornerstone of modern therapeutic strategies,
targeting a wide array of diseases with unprecedented specificity. Developing and validating …
targeting a wide array of diseases with unprecedented specificity. Developing and validating …
Rapid Quantitation of Various Therapeutic Monoclonal Antibodies Using Membranes with Fc-Specific Ligands
Therapeutic monoclonal antibodies (mAbs) provide effective treatments for many diseases,
including cancer, autoimmune disorders, and, lately, COVID-19. Monitoring the …
including cancer, autoimmune disorders, and, lately, COVID-19. Monitoring the …
In-Membrane Enrichment and Peptic Digestion to Facilitate Analysis of Monoclonal Antibody Glycosylation
The number of therapeutic monoclonal antibodies (mAbs) is growing rapidly due to their
widespread use for treating various diseases and health conditions. Assessing the …
widespread use for treating various diseases and health conditions. Assessing the …
Serum AZD7442 (tixagevimab–cilgavimab) concentrations and in vitro IC50 values predict SARS‐CoV‐2 neutralising antibody titres
LE Clegg, O Stepanov, S Matthews… - Clinical & …, 2024 - Wiley Online Library
Objectives The evolution of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐
2) necessitates rapid methods for assessing monoclonal antibody (mAb) potency against …
2) necessitates rapid methods for assessing monoclonal antibody (mAb) potency against …
Quantification of SARS-CoV-2 monoclonal IgG mass fraction by isotope dilution mass spectrometry
G Martos, M Bedu, RD Josephs, S Westwood… - Analytical and …, 2024 - Springer
The availability of serology assays to measure antibodies against the SARS coronavirus 2
(SARS-CoV-2) expanded rapidly during the Covid-19 pandemic. The interchangeable use …
(SARS-CoV-2) expanded rapidly during the Covid-19 pandemic. The interchangeable use …
Exploring peptides from toad venom for source identification by LC-MS/MS using MRM method
L Zhu, J Xu, R Gan, D Xu, J Wang, J Zhou… - Journal of Pharmaceutical …, 2024 - Elsevier
Toad venom is a traditional Chinese medicine (TCM) with various sources and wide-ranging
preparations. Previous quality assessment studies primarily concentrated on small …
preparations. Previous quality assessment studies primarily concentrated on small …