Astrocytes play important roles in numerous central nervous system disorders including
autoimmune inflammatory, hypoxic, and degenerative diseases such as Multiple Sclerosis …

Folding of the cerebral cortex is a fundamental milestone of mammalian brain evolution and
is associated with dramatic increases in size and complexity. New animal models, genetic …

An expansion of the cerebral neocortex is thought to be the foundation for the unique
intellectual abilities of humans. It has been suggested that an increase in the proliferative …

The rapid growth of the human cortex during development is accompanied by the folding of
the brain into a highly convoluted structure,,. Recent studies have focused on the genetic …

The size and extent of folding of the mammalian cerebral cortex are important factors that
influence a species' cognitive abilities and sensorimotor skills. Studies in various animal …

To understand the emergence of human higher cognition, we must understand its biological
substrate—the cerebral cortex, which considers itself the crowning achievement of evolution …

Evolutionary expansion of the human neocortex reflects increased amplification of basal
progenitors in the subventricular zone, producing more neurons during fetal corticogenesis …

One of the most prominent features of the human brain is the fabulous size of the cerebral
cortex and its intricate folding. Cortical folding takes place during embryonic development …

The human neocortex differs from that of other great apes in several notable regards,
including altered cell cycle, prolonged corticogenesis, and increased size [1–5]. Although …

Advances in the study of brain development over the last decades, especially recent findings
regarding the evolutionary expansion of the human neocortex, and large-scale analyses of …