[HTML][HTML] Opportunities and challenges for human papillomavirus vaccination in cancer

R Roden, PL Stern - Nature Reviews Cancer, 2018 - nature.com
The discovery of genotype 16 as the prototype oncogenic human papillomavirus (HPV)
initiated a quarter century of laboratory and epidemiological studies that demonstrated their …

The human papillomavirus family and its role in carcinogenesis

M Tommasino - Seminars in cancer biology, 2014 - Elsevier
Human papillomaviruses (HPVs) are a family of small double-stranded DNA viruses that
have a tropism for the epithelia of the genital and upper respiratory tracts and for the skin …

[HTML][HTML] L2, the minor capsid protein of papillomavirus

JW Wang, RBS Roden - Virology, 2013 - Elsevier
The capsid protein L2 plays major roles in both papillomavirus assembly and the infectious
process. While L1 forms the majority of the capsid and can self-assemble into empty virus …

Prophylactic HPV vaccination: past, present, and future

PE Castle, M Maza - Epidemiology & Infection, 2016 - cambridge.org
Human papillomavirus (HPV) is the necessary cause of cervical cancer, the fourth most
common cancer and cause of cancer-related death in females worldwide. HPV also causes …

Current understanding of the mechanism of HPV infection

JT Schiller, PM Day, RC Kines - Gynecologic oncology, 2010 - Elsevier
HPVs (human papillomaviruses) and other papillomaviruses have a unique mechanism of
infection that has likely evolved to limit infection to the basal cells of stratified epithelium, the …

The initial steps leading to papillomavirus infection occur on the basement membrane prior to cell surface binding

RC Kines, CD Thompson, DR Lowy… - Proceedings of the …, 2009 - National Acad Sciences
Using a murine challenge model, we previously determined that human papillomavirus
(HPV) pseudovirions initially bind preferentially to the cervicovaginal basement membrane …

Gardasil-9: A global survey of projected efficacy

L Zhai, E Tumban - Antiviral research, 2016 - Elsevier
Human papillomaviruses (HPVs) are the causative agents of human neoplasias such as
warts and cancers. There are∼ 19 HPV types associated with cancers, which has made it …

Current status and future directions for the development of human papillomavirus vaccines

R Wang, H Huang, C Yu, X Li, Y Wang… - Frontiers in …, 2024 - frontiersin.org
The development of human papillomavirus (HPV) vaccines has made substantive progress,
as represented by the approval of five prophylactic vaccines since 2006. Generally, the …

Virus-like particles for the prevention of human papillomavirus-associated malignancies

JW Wang, RBS Roden - Expert review of vaccines, 2013 - Taylor & Francis
As compared with peptide-or protein-based vaccines, naked DNA vectors and even
traditional attenuated or inactivated virus vaccines, virus-like particles (VLPs) are an …

The S100A10 subunit of the annexin A2 heterotetramer facilitates L2-mediated human papillomavirus infection

AW Woodham, DM Da Silva, JG Skeate, AB Raff… - 2012 - journals.plos.org
Mucosotropic, high-risk human papillomaviruses (HPV) are sexually transmitted viruses that
are causally associated with the development of cervical cancer. The most common high …