[HTML][HTML] Vital signs: hepatitis C treatment among insured adults—United States, 2019–2020

WW Thompson - MMWR. Morbidity and mortality weekly report, 2022 - cdc.gov
Introduction: Over 2 million adults in the United States have hepatitis C virus (HCV) infection,
and it contributes to approximately 14,000 deaths a year. Eight to 12 weeks of highly …

Current challenges and future directions for liver transplantation

P Toniutto, A Zanetto, A Ferrarese, P Burra - Liver International, 2017 - Wiley Online Library
Liver transplantation is an effective and widely used therapy for several patients with acute
and chronic liver diseases. The discrepancy between the number of patients on the waiting …

Hepatitis C infection: A multi-faceted systemic disease with clinical, patient reported and economic consequences

ZM Younossi, A Birerdinc, L Henry - Journal of hepatology, 2016 - Elsevier
Hepatitis C virus infection (HCV) affects approximately 170–200 million individuals globally.
HCV is one of the primary causes of hepatocellular carcinoma (HCC) and cirrhosis and has …

Eliciting the mitochondrial unfolded protein response by nicotinamide adenine dinucleotide repletion reverses fatty liver disease in mice

K Gariani, KJ Menzies, D Ryu, CJ Wegner… - …, 2016 - Wiley Online Library
With no approved pharmacological treatment, nonalcoholic fatty liver disease (NAFLD) is
now the most common cause of chronic liver disease in Western countries and its worldwide …

[PDF][PDF] Early detection and curative treatment of hepatocellular carcinoma: a cost‐effectiveness analysis in France and in the United States

B Cadier, J Bulsei, P Nahon, O Seror, A Laurent… - …, 2017 - Wiley Online Library
Hepatocellular carcinoma (HCC) is the leading cause of death in patients with cirrhosis.
Patients outside clinical trials seldom benefit from evidence‐based monitoring. The objective …

[HTML][HTML] A global comparison of the cost of patented cancer drugs in relation to global differences in wealth

DA Goldstein, J Clark, Y Tu, J Zhang, F Fang… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Results Cancer drug prices are highest in the United States. Cancer drugs are the least
affordable in India by a large margin. Despite lower prices than in the USA, cancer drugs are …

Duration and cost-effectiveness of hepatocellular carcinoma surveillance in hepatitis C patients after viral eradication

PP Mueller, Q Chen, T Ayer, GS Nemutlu, A Hajjar… - Journal of …, 2022 - Elsevier
Background & Aims Successful treatment of chronic hepatitis C with oral direct-acting
antivirals (DAAs) leads to virological cure, however, the subsequent risk of hepatocellular …

A blueprint for the primary prevention of cancer: targeting established, modifiable risk factors

SM Gapstur, JM Drope, EJ Jacobs… - CA: a cancer journal …, 2018 - Wiley Online Library
Abstract In the United States, it is estimated that more than 1.7 million people will be
diagnosed with cancer, and more than 600,000 will die of the disease in 2018. The financial …

Pre-clinical and clinical investigations of metabolic zonation in liver diseases: the potential of microphysiology systems

A Soto-Gutierrez, A Gough, LA Vernetti… - Experimental …, 2017 - journals.sagepub.com
The establishment of metabolic zonation within a hepatic lobule ascribes specific functions
to hepatocytes based on unique, location-dependent gene expression patterns. Recently …

Economic burden of hepatitis C infection

M Stepanova, ZM Younossi - Clinics in liver disease, 2017 - liver.theclinics.com
The studies of economic burden of chronic diseases have generally been falling behind
similar studies related to their epidemiology, morbidity, and mortality. 1 However …