Alpha-2-macroglobulin is an extracellular macromolecule mainly known for its role as a
broad-spectrum protease inhibitor. By presenting itself as an optimal substrate for …

The free radical oxidants such as reactive oxygen species, reactive nitrogen species, and
reactive sulfur species are produced inside cells through various metabolic processes. The …

It is widely acknowledged that ClO− and SCN− can have a deleterious influence on the
environment and organisms. As a result, novel approaches for detecting ClO− and SCN …

Alpha‐macroglobulins are ancient proteins that include monomeric, dimeric, and tetrameric
family members. In humans, and many other mammals, the predominant alpha …

At inflammatory sites, cytotoxic agents are released and generated from invading immune
cells and damaged tissue cells. The further fate of the inflammation highly depends on the …

Amyotrophic lateral sclerosis (ALS) is a clinical diagnosis used to define a
neurodegenerative process that involves progressive loss of voluntary muscle function and …

The drug pharmacokinetics is affected upon binding with proteins, thus making drug-protein
interactions crucial. This study investigated the interaction between enzalutamide and …

In this study, we examined for the first time the effect of the HOCl/OCl−-and H 2 O 2-induced
oxidation of Glu-plasminogen on damage to its primary structure and the biological activity of …

Silver nanoparticles (AgNPs) have several applications in nanoscience and nanomedicine
such as antibacterial, antifungal, anti-inflammatory and anti-angiogenic properties. In the …

Methotrexate (MTX) is advised in the treatment of solid tumours, hematologic malignancies
and autoimmune disorders. On reaching the circulation, 60% of MTX is bound to the proteins …