The protozoan diseases Human African Trypanosomiasis (HAT), Chagas disease (CD), and
leishmaniases span worldwide and therefore their impact is a universal concern. The …

The control of Leishmania infection relies primarily on chemotherapy till date. Resistance to
pentavalent antimonials, which have been the recommended drugs to treat cutaneous and …

The growing incidence of parasitic resistance against generic pentavalent antimonials,
specifically for visceral disease in Indian subcontinent, is a serious issue in Leishmania …

Drug discovery for neglected tropical diseases is carried out using both target-based and
phenotypic approaches. In this paper, target-based approaches are discussed, with a …

Leishmaniasis is a major public health problem and till date there are no effective vaccines
available. The control strategy relies solely on chemotherapy of the infected people …

Leishmaniasis, a group of diseases caused by hemoflagellate obligate intracellular protozoa
(trypanosomatids) from the genus Leishmania, has not received the attention it deserves …

Leishmaniasis, usually caused by the genus Leishmania, has not received the attention it
deserves and in recent times has developed into a major health problem worldwide. 1, 2 …

Protein kinases represent promising drug targets for a number of human and animal
diseases. The recent completion of the sequenced genomes of three human-infective …

Leishmaniasis is a vector borne protozoan disease and it remains a major public health
problem world-wide. Lack of an effective vaccine and vector control program makes the …

Leishmaniasis is a disease that ranges in severity from skin lesions to serious disfigurement
and fatal systemic infection. WHO estimates that the disease results in 2 million new cases a …