Cannabidiol: State of the art and new challenges for therapeutic applications
Over the past years, several lines of evidence support a therapeutic potential of Cannabis
derivatives and in particular phytocannabinoids. Δ 9-THC and cannabidiol (CBD) are the …
derivatives and in particular phytocannabinoids. Δ 9-THC and cannabidiol (CBD) are the …
Translational investigation of the therapeutic potential of cannabidiol (CBD): toward a new age
Background: Among the many cannabinoids in the cannabis plant, cannabidiol (CBD) is a
compound that does not produce the typical subjective effects of marijuana. Objectives: The …
compound that does not produce the typical subjective effects of marijuana. Objectives: The …
Immune responses regulated by cannabidiol
JM Nichols, BLF Kaplan - Cannabis and cannabinoid research, 2020 - liebertpub.com
Introduction: Cannabidiol (CBD) as Epidiolex®(GW Pharmaceuticals) was recently
approved by the US Food and Drug Administration (FDA) to treat rare forms of epilepsy in …
approved by the US Food and Drug Administration (FDA) to treat rare forms of epilepsy in …
Medical use of cannabinoids
AI Fraguas-Sánchez, AI Torres-Suárez - Drugs, 2018 - Springer
Cannabinoid receptors, endocannabinoids and the enzymes responsible for their
biosynthesis and degradation constitute the endocannabinoid system. In recent decades …
biosynthesis and degradation constitute the endocannabinoid system. In recent decades …
Medicinal properties of cannabinoids, terpenes, and flavonoids in cannabis, and benefits in migraine, headache, and pain: an update on current evidence and …
EP Baron - Headache: The Journal of Head and Face Pain, 2018 - Wiley Online Library
Background Comprehensive literature reviews of historical perspectives and evidence
supporting cannabis/cannabinoids in the treatment of pain, including migraine and …
supporting cannabis/cannabinoids in the treatment of pain, including migraine and …
Cannabidiol for neurodegenerative disorders: A comprehensive review
Despite the significant advances in neurology, the cure for neurodegenerative conditions
remains a formidable task to date. Among various factors arising from the complex etiology …
remains a formidable task to date. Among various factors arising from the complex etiology …
From phytocannabinoids to cannabinoid receptors and endocannabinoids: pleiotropic physiological and pathological roles through complex pharmacology
A Ligresti, L De Petrocellis… - Physiological …, 2016 - journals.physiology.org
Apart from having been used and misused for at least four millennia for, among others,
recreational and medicinal purposes, the cannabis plant and its most peculiar chemical …
recreational and medicinal purposes, the cannabis plant and its most peculiar chemical …
Cannabidiol (CBD) and its analogs: a review of their effects on inflammation
S Burstein - Bioorganic & medicinal chemistry, 2015 - Elsevier
First isolated from Cannabis in 1940 by Roger Adams, the structure of CBD was not
completely elucidated until 1963. Subsequent studies resulted in the pronouncement that …
completely elucidated until 1963. Subsequent studies resulted in the pronouncement that …
Cannabidiol, neuroprotection and neuropsychiatric disorders
Cannabidiol (CBD) is a non-psychotomimetic phytocannabinoid derived from Cannabis
sativa. It has possible therapeutic effects over a broad range of neuropsychiatric disorders …
sativa. It has possible therapeutic effects over a broad range of neuropsychiatric disorders …
CB1 and CB2 receptor pharmacology
AC Howlett, ME Abood - Advances in Pharmacology, 2017 - Elsevier
The CB 1 and CB 2 cannabinoid receptors (CB 1 R, CB 2 R) are members of the G protein-
coupled receptor (GPCR) family that were identified over 20 years ago. CB 1 Rs and CB 2 …
coupled receptor (GPCR) family that were identified over 20 years ago. CB 1 Rs and CB 2 …