[HTML][HTML] A review on recent drug delivery systems for posterior segment of eye

K Nayak, M Misra - Biomedicine & pharmacotherapy, 2018 - Elsevier
Eye is the unique sense organ with complex and sophisticated anatomy and physiology.
Being most instrumental for vision, it is secured by varied protective barriers; ranging from …

Polymeric implants for the treatment of intraocular eye diseases: trends in biodegradable and non-biodegradable materials

P García-Estrada, MA García-Bon, EJ López-Naranjo… - Pharmaceutics, 2021 - mdpi.com
Intraocular/Intravitreal implants constitute a relatively new method to treat eye diseases
successfully due to the possibility of releasing drugs in a controlled and prolonged way. This …

Efficacy and safety of two or more dexamethasone intravitreal implant injections for treatment of macular edema related to retinal vein occlusion (Shasta study)

A Capone Jr, MA Singer, DG Dodwell, RF Dreyer… - Retina, 2014 - journals.lww.com
Purpose: To evaluate the efficacy, safety, and reinjection interval of dexamethasone
intravitreal implant (DEX implant) in branch retinal vein occlusion and central retinal vein …

Dexamethasone implants in patients with naive or refractory diffuse diabetic macular edema

JJ Escobar-Barranco, B Pina-Marín… - …, 2015 - karger.com
Purpose: To assess the effect of dexamethasone (DEX) 0.7 mg (Ozurdex™) on refractory
and treatment-naïve diffuse diabetic macular edema. Methods: A prospective study was …

Injectable biodegradable bi-layered capsule for sustained delivery of bevacizumab in treating wet age-related macular degeneration

P Jiang, FJ Chaparro, CT Cuddington… - Journal of Controlled …, 2020 - Elsevier
Vascular endothelial growth factor (VEGF) is a key regulator of abnormal blood vessel
growth. As such, bevacizumab-based inhibition of VEGF has been the clinically adopted …

Intravitreal dexamethasone implant as a sustained release drug delivery device for the treatment of ocular diseases: a comprehensive review of the literature

C Iovino, R Mastropasqua, M Lupidi, D Bacherini… - Pharmaceutics, 2020 - mdpi.com
Drug delivery into the vitreous chamber remains a great challenge in the pharmaceutical
industry due to the complex anatomy and physiology of the eye. Intravitreal injection is the …

Repeated intravitreal dexamethasone implant (Ozurdex) for diabetic macular edema

M Scaramuzzi, G Querques, C La Spina, R Lattanzio… - Retina, 2015 - journals.lww.com
Purpose: To evaluate the effects of repeated intravitreal dexamethasone implant. Methods:
We reviewed the charts of 12 patients with diabetic macular edema, who received at least 2 …

Safety and efficacy of dexamethasone intravitreal implant for treatment of macular edema secondary to retinal vein occlusion in Chinese patients: randomized, sham …

X Li, N Wang, X Liang, G Xu, XY Li, J Jiao, J Lou… - Graefe's Archive for …, 2018 - Springer
Purpose The purpose of this study was to evaluate the safety and efficacy of dexamethasone
intravitreal implant 0.7 mg (DEX) for treatment of macular edema associated with retinal vein …

Head‐to‐head comparison of ranibizumab PRN versus single‐dose dexamethasone for branch retinal vein occlusion (COMRADE‐B)

LO Hattenbach, N Feltgen, T Bertelmann… - Acta …, 2018 - Wiley Online Library
Purpose To compare the efficacy and safety of ranibizumab 0.5 mg versus dexamethasone
0.7 mg according to their European labels in macular oedema secondary to branch retinal …

Retreatment with Ozurdex for macular edema secondary to retinal vein occlusion

G Coscas, A Augustin, F Bandello… - European Journal …, 2014 - journals.sagepub.com
Purpose To review the current practice of retreatment with Ozurdex injections in patients with
macular edema (ME) secondary to retinal vein occlusion (RVO), and to recommend simple …