Advancements in rectal drug delivery systems: clinical trials, and patents perspective

R Rathi, Sanshita, A Kumar, V Vishvakarma… - Pharmaceutics, 2022 - mdpi.com
The rectal route is an effective route for the local and systemic delivery of active
pharmaceutical ingredients. The environment of the rectum is relatively constant with low …

[HTML][HTML] Rectal route in the 21st Century to treat children

V Jannin, G Lemagnen, P Gueroult, D Larrouture… - Advanced drug delivery …, 2014 - Elsevier
The rectal route can be considered a good alternative to the oral route for the paediatric
population because these dosage forms are neither to be swallowed nor need to be taste …

An overview of in vitro dissolution/release methods for novel mucosal drug delivery systems

M Jug, A Hafner, J Lovrić, ML Kregar, I Pepić… - … of pharmaceutical and …, 2018 - Elsevier
In vitro dissolution/release tests are an important tool in the drug product development
phase as well as in its quality control and the regulatory approval process. Mucosal drug …

Preparations of rectal suppositories containing artesunate

S Persaud, S Eid, N Swiderski, I Serris, H Cho - Pharmaceutics, 2020 - mdpi.com
Rectal artesunate suppositories are a useful option for pre-referral treatment of severe
malaria, specifically in children under 6 years of age in remote malaria-endemic areas. The …

Suspension electrospinning of azithromycin loaded nanofibers

HK Güler, FC Çallioğlu - Journal of Drug Delivery Science and Technology, 2023 - Elsevier
This study presents the production of polyvinylpyrrolidone/gelatin (PVP/GEL) based and
azithromycin (AZI) loaded nanofibers via suspension electrospinning approach and …

Enhancing dissolution rate and antibacterial efficiency of azithromycin through drug-drug cocrystals with paracetamol

N Ul Islam, E Khan, M Naveed Umar, A Shah… - Antibiotics, 2021 - mdpi.com
Cocrystallization is a promising approach to alter physicochemical properties of active
pharmaceutical ingredients (hereafter abbreviated as APIs) bearing poor profile. Nowadays …

Application of green nanoemulsion to treat contaminated water (bulk aqueous solution) with azithromycin

A Hussain, O Afzal, ASA Altamimi, R Ali - Environmental Science and …, 2021 - Springer
The present work aimed to remove azithromycin (AZM) from the contaminated aqueous
system using a water/ethanol/transcutol/Capryol-90 green nanoemulsion. The drug is …

Water/transcutol/lecithin/M− 812 green cationic nanoemulsion to treat oxytetracycline contaminated aqueous bulk solution

K Venkatesan, N Haider, M Yusuf, A Hussain… - Journal of Molecular …, 2022 - Elsevier
Oxytetracycline (OXT) has been recognized as the most common veterinary medicine
discharge responsible to cause water contamination and subsequent health issues in …

Preparation and characterization of azithromycin–Aerosil 200 solid dispersions with enhanced physical stability

X Li, H Peng, B Tian, J Gou, Q Yao, X Tao, H He… - International journal of …, 2015 - Elsevier
The main purpose of this study was to investigate the feasibility of azithromycin (AZI)–Aerosil
200 solid dispersions specifically with high stability under accelerated condition (40° C/75 …

A new composite nanofibrous biomaterial development for drug delivery applications

H Kesici Güler, F Cengiz Callioglu - Express Polymer Letters, 2023 - real.mtak.hu
This study aims to produce drug delivery systems using ultrasonic spray pyrolysis (USP) and
electrospinning methods. For this purpose, the study was carried out in two steps. In the first …