In silico investigations identified Butyl Xanalterate to competently target CK2α (CSNK2A1) for therapy of chronic lymphocytic leukemia
Chronic lymphocytic leukemia (CLL) is an incurable malignancy of B-cells. In this study,
bioinformatics analyses were conducted to identify possible pathogenic roles of CK2α …
bioinformatics analyses were conducted to identify possible pathogenic roles of CK2α …
Green synthesis and anticancer potential of 1, 4-dihydropyridines-based triazole derivatives: In silico and in vitro study
A library of 1, 4-dihydropyridine-based 1, 2, 3-triazol derivatives has been designed,
synthesized, and evaluated their cytotoxic potential on colorectal adenocarcinoma (Caco-2) …
synthesized, and evaluated their cytotoxic potential on colorectal adenocarcinoma (Caco-2) …
CK2β-regulated signaling controls B cell differentiation and function
L Quotti Tubi, E Mandato, S Canovas Nunes… - Frontiers in …, 2023 - frontiersin.org
Serine-Threonine kinase CK2 supports malignant B-lymphocyte growth but its role in B-cell
development and activation is largely unknown. Here, we describe the first B-cell specific …
development and activation is largely unknown. Here, we describe the first B-cell specific …