Therapeutic application of anti-arthritis, pain-releasing, and anti-cancer effects of bee venom and its constituent compounds
Bee venom (BV) therapy (BVT), the therapeutic application of BV, has been used in
traditional medicine to treat diseases, such as arthritis, rheumatism, pain, cancerous tumors …
traditional medicine to treat diseases, such as arthritis, rheumatism, pain, cancerous tumors …
Liposomes and lipid bilayers in biosensors
Biosensors for the rapid, specific, and sensitive detection of analytes play a vital role in
healthcare, drug discovery, food safety, and environmental monitoring. Although a number …
healthcare, drug discovery, food safety, and environmental monitoring. Although a number …
Burger's medicinal chemistry and drug discovery
DJ Abraham, DP Rotella - 2003 - Wiley Online Library
Now Updated! Burger's Medicinal Chemistry, Drug Discovery and Development provides a
comprehensive source on medicinal chemistry and drug discovery and development. This …
comprehensive source on medicinal chemistry and drug discovery and development. This …
Modulation of immunity by the secreted phospholipase A2 family
M Murakami, H Sato, Y Taketomi - Immunological reviews, 2023 - Wiley Online Library
Among the phospholipase A2 (PLA2) superfamily, which typically catalyzes the sn‐2
hydrolysis of phospholipids to yield fatty acids and lysophospholipids, the secreted PLA2 …
hydrolysis of phospholipids to yield fatty acids and lysophospholipids, the secreted PLA2 …
Antibacterial actions of secreted phospholipases A2. Review
Antibacterial properties of secreted phospholipases A2 (PLA2) have emerged gradually.
Group (G) IIA PLA2 is the most potent among mammalian secreted (s) PLA2s against Gram …
Group (G) IIA PLA2 is the most potent among mammalian secreted (s) PLA2s against Gram …
Structure-based design of the first potent and selective inhibitor of human non-pancreatic secretory phospholipase A2
RW Schevitz, NJ Bach, DG Carlson… - Nature structural …, 1995 - nature.com
A lead compound obtained from a high volume human non-pancreatic secretory
phospholipase A2 (hnps-PLA2) screen has been developed into a potent inhibitor using …
phospholipase A2 (hnps-PLA2) screen has been developed into a potent inhibitor using …
[HTML][HTML] The interaction of secreted phospholipase A2-IIA with the microbiota alters its lipidome and promotes inflammation
E Doré, C Joly-Beauparlant, S Morozumi, A Mathieu… - JCI insight, 2022 - ncbi.nlm.nih.gov
Abstract Secreted phospholipase A 2-IIA (sPLA 2-IIA) hydrolyzes phospholipids to liberate
lysophospholipids and fatty acids. Given its poor activity toward eukaryotic cell membranes …
lysophospholipids and fatty acids. Given its poor activity toward eukaryotic cell membranes …
A novel anti‐inflammatory role for secretory phospholipase A2 in immune complex‐mediated arthritis
E Boilard, Y Lai, K Larabee, B Balestrieri… - EMBO molecular …, 2010 - embopress.org
Abstract Phospholipase A2 (PLA2) catalyses the release of arachidonic acid for generation
of lipid mediators of inflammation and is crucial in diverse inflammatory processes. The …
of lipid mediators of inflammation and is crucial in diverse inflammatory processes. The …
Phospholipase A2 levels in acute chest syndrome of sickle cell disease
LA Styles, CG Schalkwijk, AJ Aarsman, EP Vichinsky… - 1996 - ashpublications.org
Acute chest syndrome (ACS) is associated with significant morbidity and is the leading
cause of death in patients with sickle cell disease (SCD). Recent reports suggest that bone …
cause of death in patients with sickle cell disease (SCD). Recent reports suggest that bone …
The lipid biology of sepsis
K Amunugama, DP Pike, DA Ford - Journal of Lipid Research, 2021 - ASBMB
Sepsis, defined as the dysregulated immune response to an infection leading to organ
dysfunction, is one of the leading causes of mortality around the globe. Despite the …
dysfunction, is one of the leading causes of mortality around the globe. Despite the …