Small RNA (sRNA)-mediated RNA interference (RNAi) is a conserved regulatory
mechanism for gene expression throughout the domain Eukarya. Recent studies have …

Helminth parasites are complex metazoans that belong to different taxonomic families but
that collectively share the capacity to downregulate the host immune response directed …

Helminth parasites have a remarkable ability to persist within their mammalian hosts, which
is largely due to their secretion of molecules with immunomodulatory properties. Although …

Parasitic helminths have coevolved with humans over millennia, intricately refining and
developing an array of mechanisms to suppress or skew the host's immune system, thereby …

Schistosome infection persists for decades. Parasites are in close contact with host
peripheral blood immune cells, yet little is known about the regulatory interactions between …

Highlights•Small RNAs can transfer from pathogens or parasites into their interacting
hosts.•Plant and animal hosts can deliver small RNAs into interacting pathogens and …

Tomato yellow leaf curl virus (TYLCV) and its related begomoviruses cause fast-spreading
diseases in tomato worldwide. How this virus induces diseases remains largely unclear …

The filarial nematode Brugia malayi is an etiological agent of Lymphatic Filariasis. The
capability of B. malayi and other parasitic nematodes to modulate host biology is recognized …

The secretion of extracellular vesicles (EVs) in helminth parasites is a constitutive
mechanism that promotes survival by improving their colonization and adaptation in the host …

Background Robust protocols for the isolation of extracellular vesicles (EVs) from the rest of
their excretory-secretory products are necessary for downstream studies and application …