muscat detects subpopulation-specific state transitions from multi-sample multi-condition single-cell transcriptomics data
Single-cell RNA sequencing (scRNA-seq) has become an empowering technology to profile
the transcriptomes of individual cells on a large scale. Early analyses of differential …
the transcriptomes of individual cells on a large scale. Early analyses of differential …
A cancer biologist's primer on machine learning applications in high‐dimensional cytometry
The application of machine learning and artificial intelligence to high‐dimensional cytometry
data sets has increasingly become a staple of bioinformatic data analysis over the past …
data sets has increasingly become a staple of bioinformatic data analysis over the past …
TIGIT is upregulated by HIV-1 infection and marks a highly functional adaptive and mature subset of natural killer cells
Objective: Our objective was to investigate the mechanisms that govern natural killer (NK)-
cell responses to HIV, with a focus on specific receptor--ligand interactions involved in HIV …
cell responses to HIV, with a focus on specific receptor--ligand interactions involved in HIV …
On the discovery of subpopulation-specific state transitions from multi-sample multi-condition single-cell RNA sequencing data
Single-cell RNA sequencing (scRNA-seq) has quickly become an empowering technology
to profile the transcriptomes of individual cells on a large scale. Many early analyses of …
to profile the transcriptomes of individual cells on a large scale. Many early analyses of …
Natural killer cell phenotype is altered in HIV-exposed seronegative women
Highly exposed seronegative (HESN) individuals present a unique setting to study
mechanisms of protection against HIV acquisition. As natural killer (NK) cell activation and …
mechanisms of protection against HIV acquisition. As natural killer (NK) cell activation and …
[PDF][PDF] Algorithmic clustering of single-cell cytometry data-how unsupervised are these analyses really?
CB Pedersen, LR Olsen - Cytometry. Part A, 2020 - orbit.dtu.dk
Across single-cell technologies, including flow and mass cytometry, as well as scRNA-seq,
unsupervised clustering algorithms have become a staple of data analysis, and are often …
unsupervised clustering algorithms have become a staple of data analysis, and are often …
HLA upregulation during dengue virus infection suppresses the natural killer cell response
JL McKechnie, D Beltrán, A Pitti, L Saenz… - Frontiers in cellular …, 2019 - frontiersin.org
Dengue virus (DENV) is the most prevalent mosquito-borne virus in the world and a major
cause of morbidity in the tropics and subtropics. Upregulation of HLA class I molecules has …
cause of morbidity in the tropics and subtropics. Upregulation of HLA class I molecules has …
[HTML][HTML] Mass cytometry analysis of the NK cell receptor–ligand repertoire reveals unique differences between dengue-infected children and adults
JL McKechnie, D Beltrán, AMM Ferreira… - …, 2020 - journals.aai.org
Dengue virus (DENV) is a significant cause of morbidity in many regions of the world, with
children at the greatest risk of developing severe dengue. NK cells, characterized by their …
children at the greatest risk of developing severe dengue. NK cells, characterized by their …
CytoGLMM: conditional differential analysis for flow and mass cytometry experiments
Background Flow and mass cytometry are important modern immunology tools for
measuring expression levels of multiple proteins on single cells. The goal is to better …
measuring expression levels of multiple proteins on single cells. The goal is to better …
Characterization of the impact of daclizumab beta on circulating natural killer cells by mass cytometry
Daclizumab beta is a humanized monoclonal antibody that binds to CD25 and selectively
inhibits high-affinity IL-2 receptor signaling. As a former treatment for relapsing forms of …
inhibits high-affinity IL-2 receptor signaling. As a former treatment for relapsing forms of …