Simple Summary Three-dimensional (3D) cell culture models have been proposed as
alternatives for initial drug screening to increase drug development efficiency. In addition to …

Cancer stem cells (CSCs) as a small subpopulation in tumor bulk are believed to initiate
tumor formation and are responsible for the resistance to cancer therapy. The proliferation …

Advances of analytical methods and emerging microfluidic tools have made it possible to
investigate biological processes in living organisms in detail and reach sensitivities sufficient …

Despite major progress in elucidating the pathobiology of head and neck squamous cell
carcinoma (HNSCC), the high frequency of disease relapse correlates with unacceptably …

The investigation of human disease mechanisms is difficult due to the heterogeneity in gene
expression and the physiological state of cells in a given population. In comparison to bulk …

Microchannels in hydrogels play an essential role in enabling a smart contact lens.
However, microchannels have rarely been created in commercial hydrogel contact lenses …

Abstract 3D printing (3DP), an additive manufacturing (AM) approach allowing for rapid
prototyping and decentralized fabrication on-demand, has become a common method for …

Cancer stem cells (CSCs) play a central role in tumor progression, recurrence, and
resistance to conventional therapies, making them a critical focus in oncology research. This …

Pharmacological targeting of breast cancer stem cells (CSCs) is highly promising for the
treatment of breast cancer, as the small population of CSCs is responsible for tumor …

Cancer stem cells reside in a distinct microenvironment called niche. The reciprocal
interactions between cancer stem cells and niche contribute to the maintenance and …