Non-invasive transcranial ultrasound stimulation for neuromodulation

G Darmani, TO Bergmann, KB Pauly, CF Caskey… - Clinical …, 2022 - Elsevier
Transcranial ultrasound stimulation (TUS) holds great potential as a tool to alter neural
circuits non-invasively in both animals and humans. In contrast to established non-invasive …

[HTML][HTML] Ultrasound neuromodulation: a review of results, mechanisms and safety

J Blackmore, S Shrivastava, J Sallet, CR Butler… - Ultrasound in medicine …, 2019 - Elsevier
Ultrasonic neuromodulation is a rapidly growing field, in which low-intensity ultrasound (US)
is delivered to nervous system tissue, resulting in transient modulation of neural activity. This …

Ultrasound technologies for imaging and modulating neural activity

C Rabut, S Yoo, RC Hurt, Z Jin, H Li, H Guo, B Ling… - Neuron, 2020 - cell.com
Visualizing and perturbing neural activity on a brain-wide scale in model animals and
humans is a major goal of neuroscience technology development. Established electrical and …

Transcranial focused ultrasound modulates the activity of primary somatosensory cortex in humans

W Legon, TF Sato, A Opitz, J Mueller, A Barbour… - Nature …, 2014 - nature.com
Improved methods of noninvasively modulating human brain function are needed. Here we
probed the influence of transcranial focused ultrasound (tFUS) targeted to the human …

Neuromodulation with single‐element transcranial focused ultrasound in human thalamus

W Legon, L Ai, P Bansal, JK Mueller - Human brain mapping, 2018 - Wiley Online Library
Transcranial focused ultrasound (tFUS) has proven capable of stimulating cortical tissue in
humans. tFUS confers high spatial resolutions with deep focal lengths and as such, has the …

Low-intensity ultrasound neuromodulation: an overview of mechanisms and emerging human applications

A Fomenko, C Neudorfer, RF Dallapiazza, SK Kalia… - Brain stimulation, 2018 - Elsevier
Background There is an emerging need for noninvasive neuromodulation techniques to
improve patient outcomes while minimizing adverse events and morbidity. Low-intensity …

Ultrasound as a versatile tool for short-and long-term improvement and monitoring of brain function

DG Blackmore, D Razansky, J Götz - Neuron, 2023 - cell.com
Treating the brain with focused ultrasound (FUS) at low intensities elicits diverse responses
in neurons, astroglia, and the extracellular matrix. In combination with intravenously injected …

Ultrasound modulates ion channel currents

J Kubanek, J Shi, J Marsh, D Chen, C Deng, J Cui - Scientific reports, 2016 - nature.com
Transcranial focused ultrasound (US) has been demonstrated to stimulate neurons in
animals and humans, but the mechanism of this effect is unknown. It has been hypothesized …

A review of the current therapies, challenges, and future directions of transcranial focused ultrasound technology: advances in diagnosis and treatment

V Krishna, F Sammartino, A Rezai - JAMA neurology, 2018 - jamanetwork.com
Importance Magnetic resonance imaging–guided focused ultrasound ablation has been
approved for the treatment of refractory essential tremor and is being studied for other …

Image-guided transcranial focused ultrasound stimulates human primary somatosensory cortex

W Lee, H Kim, Y Jung, IU Song, YA Chung, SS Yoo - Scientific reports, 2015 - nature.com
Focused ultrasound (FUS) has recently been investigated as a new mode of non-invasive
brain stimulation, which offers exquisite spatial resolution and depth control. We report on …