An updated review of ciguatera fish poisoning: clinical, epidemiological, environmental, and public health management

MA Friedman, M Fernandez, LC Backer, RW Dickey… - Marine drugs, 2017 - mdpi.com
Ciguatera Fish Poisoning (CFP) is the most frequently reported seafood-toxin illness in the
world. It causes substantial human health, social, and economic impacts. The illness …

Glutathione S-transferase polymorphisms: cancer incidence and therapy

CC McIlwain, DM Townsend, KD Tew - Oncogene, 2006 - nature.com
The super family of glutathione S-transferases (GSTs) is composed of multiple isozymes with
significant evidence of functional polymorphic variation. Over the last three decades, data …

Glutathione transferases: potential targets to overcome chemoresistance in solid tumors

M Pljesa-Ercegovac, A Savic-Radojevic… - International journal of …, 2018 - mdpi.com
Multifunctional enzymes glutathione transferases (GSTs) are involved in the development of
chemoresistance, thus representing a promising target for a novel approach in cancer …

Glutathione S-transferases: an overview in cancer research

G Di Pietro, LAV Magno… - Expert opinion on drug …, 2010 - Taylor & Francis
Importance of the field: The Glutathione S-transferases (GSTs) have advanced beyond the
classic view of their role in metabolism and are encouraging scientists to assess new …

Characterization of the omega class of glutathione transferases

AK Whitbread, A Masoumi, N Tetlow, E Schmuck… - Methods in …, 2005 - Elsevier
The Omega class of cytosolic glutathione transferases was initially recognized by
bioinformatic analysis of human sequence databases, and orthologous sequences were …

Rice–arsenate interactions in hydroponics: whole genome transcriptional analysis

GJ Norton, DE Lou-Hing, AA Meharg… - Journal of experimental …, 2008 - academic.oup.com
Rice (Oryza sativa) varieties that are arsenate-tolerant (Bala) and-sensitive (Azucena) were
used to conduct a transcriptome analysis of the response of rice seedlings to sodium …

The mercapturic acid pathway

PE Hanna, MW Anders - Critical reviews in toxicology, 2019 - Taylor & Francis
The mercapturic acid pathway is a major route for the biotransformation of xenobiotic and
endobiotic electrophilic compounds and their metabolites. Mercapturic acids (N-acetyl-l …

Genetic polymorphisms influencing arsenic metabolism: evidence from Argentina

KS Engström, K Broberg, G Concha… - Environmental …, 2007 - ehp.niehs.nih.gov
The susceptibility to arsenic-induced diseases differs greatly between individuals, possibly
due to interindividual variations in As metabolism that affect retention and distribution of toxic …

Arsenic metabolism, genetic susceptibility, and risk of premalignant skin lesions in Bangladesh

H Ahsan, Y Chen, MG Kibriya, V Slavkovich… - … Biomarkers & Prevention, 2007 - AACR
We conducted a case-control study to investigate interindividual variability in susceptibility to
health effects of inorganic arsenic due to arsenic metabolism efficiency, genetic factors, and …

Glutathione S-transferase omega-1 modifies age-at-onset of Alzheimer disease and Parkinson disease

YJ Li, SA Oliveira, P Xu, ER Martin… - Human molecular …, 2003 - academic.oup.com
We previously reported genetic linkage of loci controlling age-at-onset in Alzheimer disease
(AD) and Parkinson's disease (PD) to a 15 cM region on chromosome 10q. Given the large …