Recent advances in understanding the role of mitochondrial dysfunction in
neurodegenerative diseases have expanded the opportunities for neurotherapeutics …

Due to its excellent physical and chemical properties and low price, plastic has replaced part
of the use of stone, wood and metal. The inability to degrade and improper handling have …

Background Melatonin is an indole hormone secreted primarily by the pineal gland that
showing anti-oxidant, anti-inflammatory and anti-apoptotic capacity. It can play an important …

Oxidative stress is a major contributor to the pathogenesis of various inflammatory diseases.
Accumulating evidence has shown that oxidative stress is characterized by the …

Background Human umbilical cord-derived mesenchymal stem cell (hUC-MSC) engraftment
is a promising therapy for acute ischemic stroke (AIS). However, the harsh ischemic …

Neurodegenerative diseases are characterized by the loss of homeostatic functions that
control redox and energy metabolism, neuroinflammation, and proteostasis. The …

Neural stem cells (NSCs) are self-renewing, multipotent cells which give rise to all
components of the central nervous system (CNS) during embryogenesis, but also activate in …

Due to the limited capacity of the adult mammalian brain to self-repair and regenerate,
neurological diseases, especially neurodegenerative disorders and stroke, characterized by …

Parkinson's disease (PD) is the second most prevalent neurodegenerative disorder of the
central nervous system after Alzheimer's disease. The current understanding of PD focuses …

Oxidative stress, one of the most common biological dysfunctions, is usually associated with
pathological conditions and multiple diseases in humans and animals. Chinese olive fruit …