On the central role of mitochondria dysfunction and oxidative stress in Alzheimer's disease

TO Tobore - Neurological Sciences, 2019 - Springer
Background Alzheimer's disease (AD) is the commonest cause of dementia, with
approximately 5 million new cases occurring annually. Despite decades of research, its …

Thyroid hormone levels in Alzheimer disease: a systematic review and meta-analysis

M Dolatshahi, A Salehipour, A Saghazadeh… - Endocrine, 2023 - Springer
Background and objective Thyroid hormone (TH) disturbances are perceived to contribute to
cognitive impairment and dementia. However, there is no consensus on the association …

Association of thyroid dysfunction with cognitive function: an individual participant data analysis

NA Van Vliet, D Van Heemst, OP Almeida… - JAMA internal …, 2021 - jamanetwork.com
Importance In clinical guidelines, overt and subclinical thyroid dysfunction are mentioned as
causal and treatable factors for cognitive decline. However, the scientific literature on these …

[HTML][HTML] Neuropsychiatric manifestations of thyroid diseases

V Lekurwale, S Acharya, S Shukla, S Kumar - Cureus, 2023 - ncbi.nlm.nih.gov
Thyroid disorders are known to cause neuropsychiatric manifestations. Various
neuropsychiatric manifestations are depression, dementia, mania, and autoimmune …

Association of hypothyroidism and the risk of cognitive dysfunction: a meta-analysis

Y Ye, Y Wang, S Li, J Guo, L Ding, M Liu - Journal of Clinical Medicine, 2022 - mdpi.com
Objectives: The purpose of this meta-analysis was to assess whether there is an association
between hypothyroidism and the risk of cognitive dysfunction. Methods: PubMed, Cochrane …

Association between thyroid function and Alzheimer's disease: A systematic review

PBS Figueroa, AFF Ferreira, LR Britto… - Metabolic Brain …, 2021 - Springer
Alterations in metabolic parameters have been associated with an increased risk of
dementia, among which thyroid function has gained great importance in Alzheimer's disease …

[HTML][HTML] Is hyperthyroidism a possible etiology of early onset dementia?

CJ Mathew, MT Jose, AO Elshaikh, L Shah, R Lee… - Cureus, 2020 - ncbi.nlm.nih.gov
Dementia, a disabling syndrome of the elderly characterized by the decline in memory and
cognition, is increasing in incidence and affects not only the individual but also their family …

On the etiopathogenesis and pathophysiology of Alzheimer's disease: A comprehensive theoretical review

TO Tobore - Journal of Alzheimer's Disease, 2019 - content.iospress.com
Alzheimers' disease (AD) is the most common cause of dementia, with an estimated 5
million new cases occurring annually. Among the elderly, AD shortens life expectancy …

Functional correlates of TSH, fT3 and fT4 in Alzheimer disease: a F-18 FDG PET/CT study

A Chiaravalloti, F Ursini, A Fiorentini, G Barbagallo… - Scientific Reports, 2017 - nature.com
The present study was aimed to investigate the relationships between thyroid stimulating
hormone (TSH), freeT3 (fT3) and freeT4 (fT4) and brain glucose consumption as detectable …

Correlation of thyroid dysfunction and cognitive impairments induced by subcortical ischemic vascular disease

Z Chen, X Liang, C Zhang, J Wang, G Chen… - Brain and …, 2016 - Wiley Online Library
Background To date, the relationship between thyroid dysfunction and subcortical ischemic
vascular disease (SIVD)‐induced cognitive impairments still remains elusive. Methods …