Degrons are minimal elements that mediate the interaction of proteins with degradation
machineries to promote proteolysis. Despite their central role in proteostasis, the number of …

Traditionally, protein structures have been analysed by the secondary structure architecture
and fold arrangement. An alternative approach that has shown promise is modelling …

Directed evolution is an important research activity in synthetic biology and biotechnology.
Numerous reports describe the application of tedious mutation/screening cycles for the …

The RepeatsDB database (URL: https://repeatsdb. org/) provides annotations and
classification for protein tandem repeat structures from the Protein Data Bank (PDB). Protein …

Tandem repetitions in protein sequence and structure is a fascinating subject of research
which has been a focus of study since the late 1990s. In this survey, we give an overview on …

Abstract Leucine Rich Repeat (LRR) domains, are present in hundreds of thousands of
proteins across all kingdoms of life and are typically involved in protein–protein interactions …

Ankyrin repeat containing proteins are one of the most abundant solenoid folds. Usually
implicated in specific protein-protein interactions, these proteins are readily amenable for …

Abstract RepeatsDB 2.0 (URL: http://repeatsdb. bio. unipd. it/) is an update of the database
of annotated tandem repeat protein structures. Repeat proteins are a widespread class of …

Many proteins fold into highly regular and repetitive three dimensional structures. The
analysis of structural patterns and repeated elements is fundamental to understand protein …

Background Tandem repetition of structural motifs in proteins is frequently observed across
all forms of life. Topology of repeating unit and its frequency of occurrence are associated to …