Biomedical scientists use chemistry-driven processes found in nature as an inspiration to design biomaterials as promising diagnostic tools, therapeutic solutions, or tissue …
Polymer–drug conjugates have long been a mainstay of the drug delivery field, with several conjugates successfully translated into clinical practice. The conjugation of therapeutic …
A wide variety of smart polymer systems such as thermosensitive polymers (TSPs) have been developed and applied mimicking nature. TSPs are a class of macromolecules that …
Stimuli-responsive polymers adapt to their surrounding environment. These polymers are capable of responding to a variety of external stimuli, which include optical, electrical …
The conjugation of synthetic polymers with various biomolecules provides an easy access to biohybrid materials which combine advantages from both the synthetic world and Nature …
Protein-polymer conjugates are a class of molecules that combine the stability of polymers with the diversity, specificity, and functionality of biomolecules. These bioconjugates can …
N Vanparijs, L Nuhn, BG De Geest - Chemical Society Reviews, 2017 - pubs.rsc.org
The focus of this review is on the class of transiently thermoresponsive polymers. These polymers are thermoresponsive, but gradually lose this property upon chemical …
Y Li, JA Champion - Advanced Drug Delivery Reviews, 2022 - Elsevier
Self-assembling proteins are valuable building blocks for constructing drug nanocarriers due to their self-assembly behavior, monodispersity, biocompatibility, and biodegradability …
T Trimaille, B Verrier - Pharmaceutics, 2023 - mdpi.com
Historically used for the delivery of hydrophobic drugs through core encapsulation, amphiphilic copolymer micelles have also more recently appeared as potent nano-systems …