Pyrazole-based analogs as potential antibacterial agents against methicillin-resistance staphylococcus aureus (MRSA) and its SAR elucidation
Methicillin-resistant Staphylococcus aureus (MRSA) is becoming lethal to humanity due to
easy transmission and difficult-to-treat skin and flimsy diseases. The most threatening aspect …
easy transmission and difficult-to-treat skin and flimsy diseases. The most threatening aspect …
Heterogeneous graphitic carbon nitrides in visible-light-initiated organic transformations
In recent years, g-C3N4 photocatalyst-mediated organic reactions have represented an
important mode of chemical transformations and are expected to become a crucial field at …
important mode of chemical transformations and are expected to become a crucial field at …
A key review on oxadiazole analogs as potential methicillin-resistant Staphylococcus aureus (MRSA) activity: Structure-activity relationship studies
Methicillin-resistant Staphylococcus aureus (MRSA) is becoming dangerous to human
beings due to easy transmission mode and leading to the difficult-to-treat situation. The rapid …
beings due to easy transmission mode and leading to the difficult-to-treat situation. The rapid …
Benzimidazole analogues as efficient arsenals in war against methicillin-resistance staphylococcus aureus (MRSA) and its SAR studies
Small molecule based inhibitors development is a growing field in medicinal chemistry. In
recent years, different heterocyclic derivatives have been designed to counter the infections …
recent years, different heterocyclic derivatives have been designed to counter the infections …
A novel Cas9 fusion protein promotes targeted genome editing with reduced mutational burden in primary human cells
A Carusillo, S Haider, R Schäfer, M Rhiel… - Nucleic Acids …, 2023 - academic.oup.com
Precise genome editing requires the resolution of nuclease-induced DNA double strand
breaks (DSBs) via the homology-directed repair (HDR) pathway. In mammals, this is …
breaks (DSBs) via the homology-directed repair (HDR) pathway. In mammals, this is …
Structure-activity relationship studies of thiazole agents with potential anti methicillin-resistance Staphylococcus aureus (MRSA) activity
Due to the increasing resistance of methicillin-resistant Staphylococcus aureus (MRSA) to
conventional antibiotics, further efforts are needed to develop new antimicrobial agents …
conventional antibiotics, further efforts are needed to develop new antimicrobial agents …
Fluorinated azoles as effective weapons in fight against methicillin-resistance staphylococcus aureus (MRSA) and its SAR studies
The rapid spread of Methicillin-resistant Staphylococcus aureus (MRSA) and its difficult-to-
treat skin and filmsy diseases are making MRSA a threat to human life. The most dangerous …
treat skin and filmsy diseases are making MRSA a threat to human life. The most dangerous …
Azole and chlorine: An effective combination in battle against methicillin-resistance staphylococcus aureus (MRSA) and its SAR studies
Methicillin-resistant Staphylococcus aureus (MRSA) is a threat to human life due to its fast
spread and leading to difficult-to-treat skin and filmsy diseases. The fastest-emerging MRSA …
spread and leading to difficult-to-treat skin and filmsy diseases. The fastest-emerging MRSA …
CRISPR/Cas9 library screening uncovered methylated PKP2 as a critical driver of lung cancer radioresistance by stabilizing β-catenin
C Cheng, X Pei, SW Li, J Yang, C Li, J Tang, K Hu… - Oncogene, 2021 - nature.com
Radiation resistance is a major cause of lung cancer treatment failure. Armadillo (ARM)
superfamily proteins participate in various fundamental cellular processes; however …
superfamily proteins participate in various fundamental cellular processes; however …
Modulation of DNA double-strand break repair as a strategy to improve precise genome editing
U Ray, SC Raghavan - Oncogene, 2020 - nature.com
In the present day, it is possible to incorporate targeted mutations or replace a gene using
genome editing techniques such as customisable CRISPR/Cas9 system. Although induction …
genome editing techniques such as customisable CRISPR/Cas9 system. Although induction …