Principles of DNA methylation and their implications for biology and medicine

Y Dor, H Cedar - The Lancet, 2018 - thelancet.com
DNA methylation represents an annotation system for marking the genetic text, thus
providing instruction as to how and when to read the information and control transcription …

Biological hypotheses, risk factors, and biomarkers of schizophrenia

Z Fišar - Progress in Neuro-Psychopharmacology and …, 2023 - Elsevier
Both the discovery of biomarkers of schizophrenia and the verification of biological
hypotheses of schizophrenia are an essential part of the process of understanding the …

The role of genetics in the etiology of schizophrenia

PV Gejman, AR Sanders, J Duan - Psychiatric Clinics, 2010 - psych.theclinics.com
This article introduces the reader to the genetics of schizophrenia: its background; the status
of a variety of genetic findings; new developments (which are many since the last review) 1; …

A transdisciplinary perspective of chronic stress in relation to psychopathology throughout life span development

RP Juster, G Bizik, M Picard… - Development and …, 2011 - cambridge.org
The allostatic load (AL) model represents an interdisciplinary approach to comprehensively
conceptualize and quantify chronic stress in relation to pathologies throughout the life cycle …

[HTML][HTML] Salivary biomarkers for the diagnosis and monitoring of neurological diseases

R Farah, H Haraty, Z Salame, Y Fares, DM Ojcius… - Biomedical journal, 2018 - Elsevier
Current research efforts on neurological diseases are focused on identifying novel disease
biomarkers to aid in diagnosis, provide accurate prognostic information and monitor disease …

Epigenetic modification of hippocampal Bdnf DNA in adult rats in an animal model of post-traumatic stress disorder

TL Roth, PR Zoladz, JD Sweatt, DM Diamond - Journal of psychiatric …, 2011 - Elsevier
Epigenetic alterations of the brain-derived neurotrophic factor (Bdnf) gene have been linked
with memory, stress, and neuropsychiatric disorders. Here we examined whether there was …

The dynamics of DNA methylation in schizophrenia and related psychiatric disorders

DR Grayson, A Guidotti - Neuropsychopharmacology, 2013 - nature.com
Major psychiatric disorders such as schizophrenia (SZ) and bipolar disorder (BP) with
psychosis (BP+) express a complex symptomatology characterized by positive symptoms …

Annual research review: epigenetic mechanisms and environmental shaping of the brain during sensitive periods of development

TL Roth, J David Sweatt - Journal of Child Psychology and …, 2011 - Wiley Online Library
Experiences during early development profoundly affect development of the central nervous
system (CNS) to impart either risk for or resilience to later psychopathology. Work in the …

Epigenetic modifications of GABAergic interneurons are associated with the schizophrenia-like phenotype induced by prenatal stress in mice

F Matrisciano, P Tueting, I Dalal, B Kadriu… - …, 2013 - Elsevier
Human studies suggest that a variety of prenatal stressors are related to high risk for
cognitive and behavioral abnormalities associated with psychiatric illness (Markham and …

Upregulation of dicer and microRNA expression in the dorsolateral prefrontal cortex Brodmann area 46 in schizophrenia

DM Santarelli, NJ Beveridge, PA Tooney, MJ Cairns - Biological psychiatry, 2011 - Elsevier
BACKGROUND:: MicroRNA (miRNA) are capable of regulating multitudes of target genes
and are essential factors in mediating healthy neurodevelopment. We hypothesize that …