Mechanotransduction is a fundamental ability that allows living organisms to receive and
respond to physical signals from both the external and internal environments. The …

Cancer metastasis is one of the leading causes of death worldwide, motivating research into
identifying new methods of preventing cancer metastasis. Recently there has been …

Hypertrophic scar (HS) formation is a skin fibroproliferative disease that occurs following a
cutaneous injury, leading to functional and cosmetic impairment. To date, few therapeutic …

Thrombosis is the leading complication of common human disorders including diabetes,
coronary heart disease, and infection and remains a global health burden. Current …

The mature red blood cell (RBC) lacks a nucleus and organelles characteristic of most cells,
but it is elegantly structured to perform the essential function of delivering oxygen and …

Studying and understanding the mechanism of inflammation in nucleus pulposus is the key
to understand and prevent intervertebral disc degeneration. We propose a model of …

Despite the identification of the high-incidence red cell antigen Era nearly 40 years ago, the
molecular background of this antigen, together with the other 2 members of the Er blood …

The non-selective mechanosensitive ion channel PIEZO1 controls erythrocyte volume
homeostasis. Different missense gain-of-function mutations in PIEZO1 gene have been …

Aim Diabetes is a high-risk factor for neurocognitive dysfunction. Diabetic acute
hyperglycaemia accompanied by high osmotic pressure can induce immune cell …

Erythrocytes represent at least 60% of all cells in the human body. During circulation, they
experience a huge variety of physical and chemical stimulations, such as pressure, shear …